HCSGD entry for HLA-DQB2

1. General information

Official gene symbolHLA-DQB2
Entrez ID3120
Gene full namemajor histocompatibility complex, class II, DQ beta 2
Other gene symbolsHLA-DQB1 HLA-DXB
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000139Golgi membraneTAScellular_component
GO:0002504Antigen processing and presentation of peptide or polysaccharide antigen via MHC class IIIEAbiological_process
GO:0005765Lysosomal membraneTAScellular_component
GO:0005886Plasma membraneTAScellular_component
GO:0006955Immune responseIEA NASbiological_process
GO:0010008Endosome membraneIEAcellular_component
GO:0012507ER to Golgi transport vesicle membraneTAScellular_component
GO:0016021Integral component of membraneIEAcellular_component
GO:0019221Cytokine-mediated signaling pathwayTASbiological_process
GO:0019886Antigen processing and presentation of exogenous peptide antigen via MHC class IITASbiological_process
GO:0030658Transport vesicle membraneTAScellular_component
GO:0030666Endocytic vesicle membraneTAScellular_component
GO:0030669Clathrin-coated endocytic vesicle membraneTAScellular_component
GO:0031295T cell costimulationTASbiological_process
GO:0032395MHC class II receptor activityNASmolecular_function
GO:0032588Trans-Golgi network membraneTAScellular_component
GO:0042613MHC class II protein complexIEA NAScellular_component
GO:0050852T cell receptor signaling pathwayTASbiological_process
GO:0060333Interferon-gamma-mediated signaling pathwayTASbiological_process
GO:0071556Integral component of lumenal side of endoplasmic reticulum membraneTAScellular_component
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.82360622700.52772053490.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1099226121
GSE13712_SHEARDown-0.1021175660
GSE13712_STATICDown-0.1044165956
GSE19018Up0.0729834067
GSE19899_A1Up0.1666796369
GSE19899_A2Down-0.1051588703
PubMed_21979375_A1Down-0.0473160720
PubMed_21979375_A2Up0.1623859994
GSE35957Down-0.1450114706
GSE36640Up0.1239588561
GSE54402Down-0.0624687432
GSE9593Down-0.0974864573
GSE43922--
GSE24585--
GSE37065--
GSE28863_A1Down-0.0699493772
GSE28863_A2Up0.0518289256
GSE28863_A3Up0.1511132130
GSE28863_A4Up0.0184305071
GSE48662Down-0.0450099976

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-26b-5pMIMAT0000083MIRT030178MicroarrayFunctional MTI (Weak)19088304
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.