HCSGD entry for HLA-DQB2
1. General information
Official gene symbol | HLA-DQB2 |
---|---|
Entrez ID | 3120 |
Gene full name | major histocompatibility complex, class II, DQ beta 2 |
Other gene symbols | HLA-DQB1 HLA-DXB |
Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
---|---|---|---|
GO:0000139 | Golgi membrane | TAS | cellular_component |
GO:0002504 | Antigen processing and presentation of peptide or polysaccharide antigen via MHC class II | IEA | biological_process |
GO:0005765 | Lysosomal membrane | TAS | cellular_component |
GO:0005886 | Plasma membrane | TAS | cellular_component |
GO:0006955 | Immune response | IEA NAS | biological_process |
GO:0010008 | Endosome membrane | IEA | cellular_component |
GO:0012507 | ER to Golgi transport vesicle membrane | TAS | cellular_component |
GO:0016021 | Integral component of membrane | IEA | cellular_component |
GO:0019221 | Cytokine-mediated signaling pathway | TAS | biological_process |
GO:0019886 | Antigen processing and presentation of exogenous peptide antigen via MHC class II | TAS | biological_process |
GO:0030658 | Transport vesicle membrane | TAS | cellular_component |
GO:0030666 | Endocytic vesicle membrane | TAS | cellular_component |
GO:0030669 | Clathrin-coated endocytic vesicle membrane | TAS | cellular_component |
GO:0031295 | T cell costimulation | TAS | biological_process |
GO:0032395 | MHC class II receptor activity | NAS | molecular_function |
GO:0032588 | Trans-Golgi network membrane | TAS | cellular_component |
GO:0042613 | MHC class II protein complex | IEA NAS | cellular_component |
GO:0050852 | T cell receptor signaling pathway | TAS | biological_process |
GO:0060333 | Interferon-gamma-mediated signaling pathway | TAS | biological_process |
GO:0071556 | Integral component of lumenal side of endoplasmic reticulum membrane | TAS | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
p-value up | p-value down | FDR up | FDR down |
---|---|---|---|
0.8236062270 | 0.5277205349 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
Data source | Up or down | Log fold change |
---|---|---|
GSE11954 | Down | -0.1099226121 |
GSE13712_SHEAR | Down | -0.1021175660 |
GSE13712_STATIC | Down | -0.1044165956 |
GSE19018 | Up | 0.0729834067 |
GSE19899_A1 | Up | 0.1666796369 |
GSE19899_A2 | Down | -0.1051588703 |
PubMed_21979375_A1 | Down | -0.0473160720 |
PubMed_21979375_A2 | Up | 0.1623859994 |
GSE35957 | Down | -0.1450114706 |
GSE36640 | Up | 0.1239588561 |
GSE54402 | Down | -0.0624687432 |
GSE9593 | Down | -0.0974864573 |
GSE43922 | - | - |
GSE24585 | - | - |
GSE37065 | - | - |
GSE28863_A1 | Down | -0.0699493772 |
GSE28863_A2 | Up | 0.0518289256 |
GSE28863_A3 | Up | 0.1511132130 |
GSE28863_A4 | Up | 0.0184305071 |
GSE48662 | Down | -0.0450099976 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
---|---|---|---|---|---|
hsa-miR-26b-5p | MIMAT0000083 | MIRT030178 | Microarray | Functional MTI (Weak) | 19088304 |
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