HCSGD entry for HLA-DOA

1. General information

Official gene symbolHLA-DOA
Entrez ID3111
Gene full namemajor histocompatibility complex, class II, DO alpha
Other gene symbolsHLA-DNA HLA-DZA HLADZ
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0002504Antigen processing and presentation of peptide or polysaccharide antigen via MHC class IIIEAbiological_process
GO:0005765Lysosomal membraneTAScellular_component
GO:0005886Plasma membraneTAScellular_component
GO:0006955Immune responseIEAbiological_process
GO:0007165Signal transductionTASbiological_process
GO:0010008Endosome membraneIEAcellular_component
GO:0016021Integral component of membraneIEAcellular_component
GO:0019886Antigen processing and presentation of exogenous peptide antigen via MHC class IITASbiological_process
GO:0032395MHC class II receptor activityTASmolecular_function
GO:0042613MHC class II protein complexIEAcellular_component
GO:0045580Regulation of T cell differentiationIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.52200202500.92476279020.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0603444914
GSE13712_SHEARUp0.0852126451
GSE13712_STATICDown-0.1958759369
GSE19018Up0.1056723373
GSE19899_A1Up0.0300080475
GSE19899_A2Up0.0702773424
PubMed_21979375_A1Up0.1865110240
PubMed_21979375_A2Up0.0173381098
GSE35957Up0.0466469332
GSE36640Down-0.0233393644
GSE54402Up0.0270349317
GSE9593Up0.0485468365
GSE43922Up0.0409210548
GSE24585Up0.4709179643
GSE37065Up0.0007792526
GSE28863_A1Down-0.1177222638
GSE28863_A2Up0.0195308081
GSE28863_A3Up0.2312546073
GSE28863_A4Up0.1012943645
GSE48662Up0.0141484720

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.