HCSGD entry for HLA-DOA

1. General information

Official gene symbolHLA-DOA
Entrez ID3111
Gene full namemajor histocompatibility complex, class II, DO alpha
Other gene symbolsHLA-DNA HLA-DZA HLADZ
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0002504Antigen processing and presentation of peptide or polysaccharide antigen via MHC class IIIEAbiological_process
GO:0005765Lysosomal membraneTAScellular_component
GO:0005886Plasma membraneTAScellular_component
GO:0006955Immune responseIEAbiological_process
GO:0007165Signal transductionTASbiological_process
GO:0010008Endosome membraneIEAcellular_component
GO:0016021Integral component of membraneIEAcellular_component
GO:0019886Antigen processing and presentation of exogenous peptide antigen via MHC class IITASbiological_process
GO:0032395MHC class II receptor activityTASmolecular_function
GO:0042613MHC class II protein complexIEAcellular_component
GO:0045580Regulation of T cell differentiationIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.52200202500.92476279020.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0603444914
GSE13712_SHEARUp0.0852126451
GSE13712_STATICDown-0.1958759369
GSE19018Up0.1056723373
GSE19899_A1Up0.0300080475
GSE19899_A2Up0.0702773424
PubMed_21979375_A1Up0.1865110240
PubMed_21979375_A2Up0.0173381098
GSE35957Up0.0466469332
GSE36640Down-0.0233393644
GSE54402Up0.0270349317
GSE9593Up0.0485468365
GSE43922Up0.0409210548
GSE24585Up0.4709179643
GSE37065Up0.0007792526
GSE28863_A1Down-0.1177222638
GSE28863_A2Up0.0195308081
GSE28863_A3Up0.2312546073
GSE28863_A4Up0.1012943645
GSE48662Up0.0141484720

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.