HCSGD entry for HLA-DMA

1. General information

Official gene symbolHLA-DMA
Entrez ID3108
Gene full namemajor histocompatibility complex, class II, DM alpha
Other gene symbolsD6S222E DMA HLADM RING6
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0002504Antigen processing and presentation of peptide or polysaccharide antigen via MHC class IIIEAbiological_process
GO:0005765Lysosomal membraneIEA TAScellular_component
GO:0005771Multivesicular bodyIEAcellular_component
GO:0006461Protein complex assemblyIEAbiological_process
GO:0006955Immune responseIEAbiological_process
GO:0010008Endosome membraneIEAcellular_component
GO:0015031Protein transportIEAbiological_process
GO:0016021Integral component of membraneIEAcellular_component
GO:0016064Immunoglobulin mediated immune responseIEAbiological_process
GO:0019886Antigen processing and presentation of exogenous peptide antigen via MHC class IIIEA TASbiological_process
GO:0031902Late endosome membraneIEAcellular_component
GO:0042613MHC class II protein complexIEAcellular_component
GO:0045059Positive thymic T cell selectionIEAbiological_process
GO:0045582Positive regulation of T cell differentiationIEAbiological_process
GO:0048839Inner ear developmentIEAbiological_process
GO:0050778Positive regulation of immune responseIEAbiological_process
GO:0051085Chaperone mediated protein folding requiring cofactorIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.22367107250.00723599030.90402897930.1699777877

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.3520204373
GSE13712_SHEARUp0.4163153707
GSE13712_STATICUp0.4731030520
GSE19018Down-0.2177434950
GSE19899_A1Down-0.3178445790
GSE19899_A2Down-2.8511035748
PubMed_21979375_A1Down-1.0046721233
PubMed_21979375_A2Down-1.4401619179
GSE35957Down-1.9001047975
GSE36640Up1.1512263806
GSE54402Down-0.5347895143
GSE9593Up1.0285785767
GSE43922Down-1.8988550285
GSE24585Up0.5382248514
GSE37065Up0.3948399953
GSE28863_A1Up0.1334537159
GSE28863_A2Up0.1310653712
GSE28863_A3Down-0.3751746475
GSE28863_A4Down-0.1953745988
GSE48662Up0.1945158860

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT018266MicroarrayFunctional MTI (Weak)18185580
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.