HCSGD entry for HLA-DMA
1. General information
| Official gene symbol | HLA-DMA |
|---|---|
| Entrez ID | 3108 |
| Gene full name | major histocompatibility complex, class II, DM alpha |
| Other gene symbols | D6S222E DMA HLADM RING6 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0002504 | Antigen processing and presentation of peptide or polysaccharide antigen via MHC class II | IEA | biological_process |
| GO:0005765 | Lysosomal membrane | IEA TAS | cellular_component |
| GO:0005771 | Multivesicular body | IEA | cellular_component |
| GO:0006461 | Protein complex assembly | IEA | biological_process |
| GO:0006955 | Immune response | IEA | biological_process |
| GO:0010008 | Endosome membrane | IEA | cellular_component |
| GO:0015031 | Protein transport | IEA | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0016064 | Immunoglobulin mediated immune response | IEA | biological_process |
| GO:0019886 | Antigen processing and presentation of exogenous peptide antigen via MHC class II | IEA TAS | biological_process |
| GO:0031902 | Late endosome membrane | IEA | cellular_component |
| GO:0042613 | MHC class II protein complex | IEA | cellular_component |
| GO:0045059 | Positive thymic T cell selection | IEA | biological_process |
| GO:0045582 | Positive regulation of T cell differentiation | IEA | biological_process |
| GO:0048839 | Inner ear development | IEA | biological_process |
| GO:0050778 | Positive regulation of immune response | IEA | biological_process |
| GO:0051085 | Chaperone mediated protein folding requiring cofactor | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2236710725 | 0.0072359903 | 0.9040289793 | 0.1699777877 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.3520204373 |
| GSE13712_SHEAR | Up | 0.4163153707 |
| GSE13712_STATIC | Up | 0.4731030520 |
| GSE19018 | Down | -0.2177434950 |
| GSE19899_A1 | Down | -0.3178445790 |
| GSE19899_A2 | Down | -2.8511035748 |
| PubMed_21979375_A1 | Down | -1.0046721233 |
| PubMed_21979375_A2 | Down | -1.4401619179 |
| GSE35957 | Down | -1.9001047975 |
| GSE36640 | Up | 1.1512263806 |
| GSE54402 | Down | -0.5347895143 |
| GSE9593 | Up | 1.0285785767 |
| GSE43922 | Down | -1.8988550285 |
| GSE24585 | Up | 0.5382248514 |
| GSE37065 | Up | 0.3948399953 |
| GSE28863_A1 | Up | 0.1334537159 |
| GSE28863_A2 | Up | 0.1310653712 |
| GSE28863_A3 | Down | -0.3751746475 |
| GSE28863_A4 | Down | -0.1953745988 |
| GSE48662 | Up | 0.1945158860 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT018266 | Microarray | Functional MTI (Weak) | 18185580 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
