HCSGD entry for KCNIP3
1. General information
| Official gene symbol | KCNIP3 |
|---|---|
| Entrez ID | 30818 |
| Gene full name | Kv channel interacting protein 3, calsenilin |
| Other gene symbols | CSEN DREAM KCHIP3 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000122 | Negative regulation of transcription from RNA polymerase II promoter | IEA | biological_process |
| GO:0003677 | DNA binding | TAS | molecular_function |
| GO:0003714 | Transcription corepressor activity | TAS | molecular_function |
| GO:0005244 | Voltage-gated ion channel activity | IEA | molecular_function |
| GO:0005267 | Potassium channel activity | IEA | molecular_function |
| GO:0005509 | Calcium ion binding | IEA | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0005783 | Endoplasmic reticulum | IEA | cellular_component |
| GO:0005794 | Golgi apparatus | IEA | cellular_component |
| GO:0005829 | Cytosol | IEA | cellular_component |
| GO:0005886 | Plasma membrane | IEA | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0006357 | Regulation of transcription from RNA polymerase II promoter | TAS | biological_process |
| GO:0006886 | Intracellular protein transport | IEA | biological_process |
| GO:0006915 | Apoptotic process | IEA | biological_process |
| GO:0007165 | Signal transduction | TAS | biological_process |
| GO:0008022 | Protein C-terminus binding | IEA | molecular_function |
| GO:0015459 | Potassium channel regulator activity | IEA | molecular_function |
| GO:0019233 | Sensory perception of pain | IEA | biological_process |
| GO:0030425 | Dendrite | IEA | cellular_component |
| GO:0032993 | Protein-DNA complex | IEA | cellular_component |
| GO:0043523 | Regulation of neuron apoptotic process | IEA | biological_process |
| GO:0043565 | Sequence-specific DNA binding | IEA | molecular_function |
| GO:0043679 | Axon terminus | IEA | cellular_component |
| GO:0044325 | Ion channel binding | IEA | molecular_function |
| GO:0048266 | Behavioral response to pain | IEA | biological_process |
| GO:0048306 | Calcium-dependent protein binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9281218381 | 0.2549587364 | 0.9999902473 | 0.9683986869 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0115352733 |
| GSE13712_SHEAR | Down | -0.0812048849 |
| GSE13712_STATIC | Down | -0.0678276297 |
| GSE19018 | Up | 0.0343571936 |
| GSE19899_A1 | Up | 0.0997036109 |
| GSE19899_A2 | Up | 0.0650405705 |
| PubMed_21979375_A1 | Up | 0.0953831802 |
| PubMed_21979375_A2 | Down | -0.1018915065 |
| GSE35957 | Down | -0.0358945992 |
| GSE36640 | Up | 0.0571492201 |
| GSE54402 | Down | -0.0053409934 |
| GSE9593 | Up | 0.2210017545 |
| GSE43922 | Down | -0.1596239814 |
| GSE24585 | Down | -0.4951096526 |
| GSE37065 | Down | -0.2089039883 |
| GSE28863_A1 | Down | -0.3285038922 |
| GSE28863_A2 | Up | 0.2272497983 |
| GSE28863_A3 | Down | -0.0037268799 |
| GSE28863_A4 | Down | -0.1337530912 |
| GSE48662 | Down | -0.0710025470 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
