HCSGD entry for KCNIP3


1. General information

Official gene symbolKCNIP3
Entrez ID30818
Gene full nameKv channel interacting protein 3, calsenilin
Other gene symbolsCSEN DREAM KCHIP3
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000122Negative regulation of transcription from RNA polymerase II promoterIEAbiological_process
GO:0003677DNA bindingTASmolecular_function
GO:0003714Transcription corepressor activityTASmolecular_function
GO:0005244Voltage-gated ion channel activityIEAmolecular_function
GO:0005267Potassium channel activityIEAmolecular_function
GO:0005509Calcium ion bindingIEAmolecular_function
GO:0005634NucleusIEAcellular_component
GO:0005783Endoplasmic reticulumIEAcellular_component
GO:0005794Golgi apparatusIEAcellular_component
GO:0005829CytosolIEAcellular_component
GO:0005886Plasma membraneIEAcellular_component
GO:0006351Transcription, DNA-templatedIEAbiological_process
GO:0006357Regulation of transcription from RNA polymerase II promoterTASbiological_process
GO:0006886Intracellular protein transportIEAbiological_process
GO:0006915Apoptotic processIEAbiological_process
GO:0007165Signal transductionTASbiological_process
GO:0008022Protein C-terminus bindingIEAmolecular_function
GO:0015459Potassium channel regulator activityIEAmolecular_function
GO:0019233Sensory perception of painIEAbiological_process
GO:0030425DendriteIEAcellular_component
GO:0032993Protein-DNA complexIEAcellular_component
GO:0043523Regulation of neuron apoptotic processIEAbiological_process
GO:0043565Sequence-specific DNA bindingIEAmolecular_function
GO:0043679Axon terminusIEAcellular_component
GO:0044325Ion channel bindingIEAmolecular_function
GO:0048266Behavioral response to painIEAbiological_process
GO:0048306Calcium-dependent protein bindingIEAmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.92812183810.25495873640.99999024730.9683986869

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0115352733
GSE13712_SHEARDown-0.0812048849
GSE13712_STATICDown-0.0678276297
GSE19018Up0.0343571936
GSE19899_A1Up0.0997036109
GSE19899_A2Up0.0650405705
PubMed_21979375_A1Up0.0953831802
PubMed_21979375_A2Down-0.1018915065
GSE35957Down-0.0358945992
GSE36640Up0.0571492201
GSE54402Down-0.0053409934
GSE9593Up0.2210017545
GSE43922Down-0.1596239814
GSE24585Down-0.4951096526
GSE37065Down-0.2089039883
GSE28863_A1Down-0.3285038922
GSE28863_A2Up0.2272497983
GSE28863_A3Down-0.0037268799
GSE28863_A4Down-0.1337530912
GSE48662Down-0.0710025470

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.