HCSGD entry for ACAA1

1. General information

Official gene symbolACAA1
Entrez ID30
Gene full nameacetyl-CoA acyltransferase 1
Other gene symbolsACAA PTHIO THIO
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000038Very long-chain fatty acid metabolic processIMPbiological_process
GO:0003988Acetyl-CoA C-acyltransferase activityIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005777PeroxisomeIDAcellular_component
GO:0005782Peroxisomal matrixTAScellular_component
GO:0006635Fatty acid beta-oxidationIMPbiological_process
GO:0008206Bile acid metabolic processIMPbiological_process
GO:0016401Palmitoyl-CoA oxidase activityIMPmolecular_function
GO:0016747Transferase activity, transferring acyl groups other than amino-acyl groupsIEAmolecular_function
GO:0033540Fatty acid beta-oxidation using acyl-CoA oxidaseTASbiological_process
GO:0033559Unsaturated fatty acid metabolic processTASbiological_process
GO:0036109Alpha-linolenic acid metabolic processTASbiological_process
GO:0043231Intracellular membrane-bounded organelleIDAcellular_component
GO:0044255Cellular lipid metabolic processTASbiological_process
GO:0044281Small molecule metabolic processTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.10054788190.85565129360.66138088461.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.6272953880
GSE13712_SHEARDown-0.0561528633
GSE13712_STATICUp0.2720420527
GSE19018Up0.0299439947
GSE19899_A1Down-0.0192810630
GSE19899_A2Up0.7842217053
PubMed_21979375_A1Down-0.1331471905
PubMed_21979375_A2Up0.5129905373
GSE35957Up0.2178057441
GSE36640Up1.0443037285
GSE54402Up0.0325665101
GSE9593Up0.2200084497
GSE43922Down-0.1512131609
GSE24585Down-0.0051001499
GSE37065Down-0.0583087983
GSE28863_A1Down-0.0677826586
GSE28863_A2Down-0.1953349890
GSE28863_A3Down-0.1436946600
GSE28863_A4Up0.0535531908
GSE48662Up0.1285493030

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

TrimetazidineDB09069 -

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-877-3pMIMAT0004950MIRT036918CLASHFunctional MTI (Weak)23622248
hsa-miR-10a-5pMIMAT0000253MIRT047559CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.