HCSGD entry for GUCA2B

1. General information

Official gene symbolGUCA2B
Entrez ID2981
Gene full nameguanylate cyclase activator 2B (uroguanylin)
Other gene symbolsGCAP-II UGN
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005576Extracellular regionIEAcellular_component
GO:0006182CGMP biosynthetic processIEAbiological_process
GO:0007588ExcretionIEAbiological_process
GO:0007589Body fluid secretionIEAbiological_process
GO:0008048Calcium sensitive guanylate cyclase activator activityTASmolecular_function
GO:0031279Regulation of cyclase activityTASbiological_process
GO:0031282Regulation of guanylate cyclase activityTASbiological_process
GO:0031284Positive regulation of guanylate cyclase activityTASbiological_process
GO:0043085Positive regulation of catalytic activityTASbiological_process
GO:0045776Negative regulation of blood pressureIEAbiological_process
GO:0050790Regulation of catalytic activityTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.19517831390.88304298850.85607205471.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0710880504
GSE13712_SHEARDown-0.1620805500
GSE13712_STATICUp0.1949442167
GSE19018Down-0.0729855507
GSE19899_A1Up0.0565917292
GSE19899_A2Up0.1385425689
PubMed_21979375_A1Down-0.2161138559
PubMed_21979375_A2Down-0.1326306905
GSE35957Up0.0417414907
GSE36640Down-0.0305259095
GSE54402Down-0.0141526547
GSE9593Up0.0311942127
GSE43922Up0.1394013340
GSE24585Up0.0869026868
GSE37065Down-0.1356366544
GSE28863_A1Down-0.0991062593
GSE28863_A2Up0.2715418905
GSE28863_A3Up0.3723260933
GSE28863_A4Up0.0585978859
GSE48662Up1.2964931804

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT017706MicroarrayFunctional MTI (Weak)18185580
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.