HCSGD entry for GUCA2B

1. General information

Official gene symbolGUCA2B
Entrez ID2981
Gene full nameguanylate cyclase activator 2B (uroguanylin)
Other gene symbolsGCAP-II UGN
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005576Extracellular regionIEAcellular_component
GO:0006182CGMP biosynthetic processIEAbiological_process
GO:0007588ExcretionIEAbiological_process
GO:0007589Body fluid secretionIEAbiological_process
GO:0008048Calcium sensitive guanylate cyclase activator activityTASmolecular_function
GO:0031279Regulation of cyclase activityTASbiological_process
GO:0031282Regulation of guanylate cyclase activityTASbiological_process
GO:0031284Positive regulation of guanylate cyclase activityTASbiological_process
GO:0043085Positive regulation of catalytic activityTASbiological_process
GO:0045776Negative regulation of blood pressureIEAbiological_process
GO:0050790Regulation of catalytic activityTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.19517831390.88304298850.85607205471.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0710880504
GSE13712_SHEARDown-0.1620805500
GSE13712_STATICUp0.1949442167
GSE19018Down-0.0729855507
GSE19899_A1Up0.0565917292
GSE19899_A2Up0.1385425689
PubMed_21979375_A1Down-0.2161138559
PubMed_21979375_A2Down-0.1326306905
GSE35957Up0.0417414907
GSE36640Down-0.0305259095
GSE54402Down-0.0141526547
GSE9593Up0.0311942127
GSE43922Up0.1394013340
GSE24585Up0.0869026868
GSE37065Down-0.1356366544
GSE28863_A1Down-0.0991062593
GSE28863_A2Up0.2715418905
GSE28863_A3Up0.3723260933
GSE28863_A4Up0.0585978859
GSE48662Up1.2964931804

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT017706MicroarrayFunctional MTI (Weak)18185580
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.