HCSGD entry for SLC25A6


1. General information

Official gene symbolSLC25A6
Entrez ID293
Gene full namesolute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6
Other gene symbolsAAC3 ANT3 ANT3Y
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005215Transporter activityIEAmolecular_function
GO:0005471ATP:ADP antiporter activityNASmolecular_function
GO:0005743Mitochondrial inner membraneIEA TAScellular_component
GO:0005744Mitochondrial inner membrane presequence translocase complexTAScellular_component
GO:0006112Energy reserve metabolic processTASbiological_process
GO:0006626Protein targeting to mitochondrionTASbiological_process
GO:0006820Anion transportNASbiological_process
GO:0006915Apoptotic processIEAbiological_process
GO:0015711Organic anion transportNASbiological_process
GO:0015748Organophosphate ester transportNASbiological_process
GO:0015860Purine nucleoside transmembrane transportNASbiological_process
GO:0015865Purine nucleotide transportNASbiological_process
GO:0015866ADP transportNASbiological_process
GO:0015867ATP transportNASbiological_process
GO:0015931Nucleobase-containing compound transportNASbiological_process
GO:0016021Integral component of membraneIEAcellular_component
GO:0016032Viral processTASbiological_process
GO:0019048Modulation by virus of host morphology or physiologyTASbiological_process
GO:0019058Viral life cycleTASbiological_process
GO:0034220Ion transmembrane transportNASbiological_process
GO:0044267Cellular protein metabolic processTASbiological_process
GO:0044281Small molecule metabolic processTASbiological_process
GO:0046732Active induction of host immune response by virusTASbiological_process
GO:0050796Regulation of insulin secretionTASbiological_process
GO:0051503Adenine nucleotide transportNASbiological_process
GO:0055085Transmembrane transportIEAbiological_process
GO:1901264Carbohydrate derivative transportNASbiological_process
GO:1901642Nucleoside transmembrane transportNASbiological_process
GO:1901679Nucleotide transmembrane transportNASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.97862424300.05293131720.99999024730.4340438941

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0933827713
GSE13712_SHEARDown-0.5211102069
GSE13712_STATICDown-0.4318576887
GSE19018Down-0.2735041594
GSE19899_A1Down-0.2348243223
GSE19899_A2Up0.1441092314
PubMed_21979375_A1Up0.0126380368
PubMed_21979375_A2Down-0.4057918264
GSE35957Down-0.2561251248
GSE36640Down-0.4743669970
GSE54402Up0.3271488035
GSE9593Up0.0108335334
GSE43922Down-0.0573141113
GSE24585Down-0.3100722788
GSE37065Down-0.5013075638
GSE28863_A1--
GSE28863_A2--
GSE28863_A3--
GSE28863_A4--
GSE48662Up0.0452063098

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-16-5pMIMAT0000069MIRT031609ProteomicsFunctional MTI (Weak)18668040
hsa-miR-421MIMAT0003339MIRT039389CLASHFunctional MTI (Weak)23622248
hsa-miR-423-3pMIMAT0001340MIRT042493CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.