HCSGD entry for SLC25A6
1. General information
| Official gene symbol | SLC25A6 |
|---|---|
| Entrez ID | 293 |
| Gene full name | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6 |
| Other gene symbols | AAC3 ANT3 ANT3Y |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005215 | Transporter activity | IEA | molecular_function |
| GO:0005471 | ATP:ADP antiporter activity | NAS | molecular_function |
| GO:0005743 | Mitochondrial inner membrane | IEA TAS | cellular_component |
| GO:0005744 | Mitochondrial inner membrane presequence translocase complex | TAS | cellular_component |
| GO:0006112 | Energy reserve metabolic process | TAS | biological_process |
| GO:0006626 | Protein targeting to mitochondrion | TAS | biological_process |
| GO:0006820 | Anion transport | NAS | biological_process |
| GO:0006915 | Apoptotic process | IEA | biological_process |
| GO:0015711 | Organic anion transport | NAS | biological_process |
| GO:0015748 | Organophosphate ester transport | NAS | biological_process |
| GO:0015860 | Purine nucleoside transmembrane transport | NAS | biological_process |
| GO:0015865 | Purine nucleotide transport | NAS | biological_process |
| GO:0015866 | ADP transport | NAS | biological_process |
| GO:0015867 | ATP transport | NAS | biological_process |
| GO:0015931 | Nucleobase-containing compound transport | NAS | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0016032 | Viral process | TAS | biological_process |
| GO:0019048 | Modulation by virus of host morphology or physiology | TAS | biological_process |
| GO:0019058 | Viral life cycle | TAS | biological_process |
| GO:0034220 | Ion transmembrane transport | NAS | biological_process |
| GO:0044267 | Cellular protein metabolic process | TAS | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0046732 | Active induction of host immune response by virus | TAS | biological_process |
| GO:0050796 | Regulation of insulin secretion | TAS | biological_process |
| GO:0051503 | Adenine nucleotide transport | NAS | biological_process |
| GO:0055085 | Transmembrane transport | IEA | biological_process |
| GO:1901264 | Carbohydrate derivative transport | NAS | biological_process |
| GO:1901642 | Nucleoside transmembrane transport | NAS | biological_process |
| GO:1901679 | Nucleotide transmembrane transport | NAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9786242430 | 0.0529313172 | 0.9999902473 | 0.4340438941 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0933827713 |
| GSE13712_SHEAR | Down | -0.5211102069 |
| GSE13712_STATIC | Down | -0.4318576887 |
| GSE19018 | Down | -0.2735041594 |
| GSE19899_A1 | Down | -0.2348243223 |
| GSE19899_A2 | Up | 0.1441092314 |
| PubMed_21979375_A1 | Up | 0.0126380368 |
| PubMed_21979375_A2 | Down | -0.4057918264 |
| GSE35957 | Down | -0.2561251248 |
| GSE36640 | Down | -0.4743669970 |
| GSE54402 | Up | 0.3271488035 |
| GSE9593 | Up | 0.0108335334 |
| GSE43922 | Down | -0.0573141113 |
| GSE24585 | Down | -0.3100722788 |
| GSE37065 | Down | -0.5013075638 |
| GSE28863_A1 | - | - |
| GSE28863_A2 | - | - |
| GSE28863_A3 | - | - |
| GSE28863_A4 | - | - |
| GSE48662 | Up | 0.0452063098 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-16-5p | MIMAT0000069 | MIRT031609 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-421 | MIMAT0003339 | MIRT039389 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-423-3p | MIMAT0001340 | MIRT042493 | CLASH | Functional MTI (Weak) | 23622248 |
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