HCSGD entry for GRM4

1. General information

Official gene symbolGRM4
Entrez ID2914
Gene full nameglutamate receptor, metabotropic 4
Other gene symbolsGPRC1D MGLUR4 mGlu4
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000187Activation of MAPK activityIDAbiological_process
GO:0004930G-protein coupled receptor activityIEA IMPmolecular_function
GO:0005516Calmodulin bindingIEAmolecular_function
GO:0005622IntracellularIDAcellular_component
GO:0005886Plasma membraneIEA TAScellular_component
GO:0005887Integral component of plasma membraneIDAcellular_component
GO:0007196Adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathwayIMPbiological_process
GO:0007268Synaptic transmissionTASbiological_process
GO:0007269Neurotransmitter secretionTASbiological_process
GO:0007612LearningIEAbiological_process
GO:0008066Glutamate receptor activityIMPmolecular_function
GO:0016021Integral component of membraneIEAcellular_component
GO:0031410Cytoplasmic vesicleIDAcellular_component
GO:0043195Terminal boutonIEAcellular_component
GO:0043198Dendritic shaftIEAcellular_component
GO:0043410Positive regulation of MAPK cascadeIEPbiological_process
GO:0043523Regulation of neuron apoptotic processTASbiological_process
GO:0048306Calcium-dependent protein bindingIEAmolecular_function
GO:0048787Presynaptic active zone membraneIEAcellular_component
Entries Per Page
Displaying Page of

4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.46440101440.76960518220.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.2438523172
GSE13712_SHEARUp0.1752148908
GSE13712_STATICUp0.1667615216
GSE19018Down-0.0527115836
GSE19899_A1Up0.0108197963
GSE19899_A2Up0.0543532978
PubMed_21979375_A1Up0.1157722337
PubMed_21979375_A2Down-0.2028117799
GSE35957Up0.0273706899
GSE36640Down-0.0148502854
GSE54402Up0.0564791531
GSE9593Down-0.1186421121
GSE43922Up0.1489533097
GSE24585Up0.1800212420
GSE37065Down-0.0842285971
GSE28863_A1Up0.0839092051
GSE28863_A2Up0.3952704621
GSE28863_A3Up0.1731023964
GSE28863_A4Down-0.0883851703
GSE48662Up0.2215093917

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

L-Glutamic AcidDB00142 NUTR00027

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.