HCSGD entry for GRM1

1. General information

Official gene symbolGRM1
Entrez ID2911
Gene full nameglutamate receptor, metabotropic 1
Other gene symbolsGPRC1A MGLU1 MGLUR1 SCAR13
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000186Activation of MAPKK activityIEAbiological_process
GO:0000187Activation of MAPK activityIEAbiological_process
GO:0004930G-protein coupled receptor activityIEA TASmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIEAcellular_component
GO:0005886Plasma membraneIEA TAScellular_component
GO:0005887Integral component of plasma membraneTAScellular_component
GO:0007186G-protein coupled receptor signaling pathwayTASbiological_process
GO:0007268Synaptic transmissionTASbiological_process
GO:0007626Locomotory behaviorIEAbiological_process
GO:0008066Glutamate receptor activityIDA TASmolecular_function
GO:0008219Cell deathIEAbiological_process
GO:0014069Postsynaptic densityIEAcellular_component
GO:0016021Integral component of membraneIEAcellular_component
GO:0019233Sensory perception of painIEAbiological_process
GO:0030425DendriteIEAcellular_component
GO:0038038G-protein coupled receptor homodimeric complexIPIcellular_component
GO:0051930Regulation of sensory perception of painIEAbiological_process
GO:0071257Cellular response to electrical stimulusIEAbiological_process
Entries Per Page
Displaying Page of

4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.55007143350.95328386840.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1625403726
GSE13712_SHEARUp0.0060402110
GSE13712_STATICUp0.0325087069
GSE19018Up0.1984450440
GSE19899_A1Up0.0132980237
GSE19899_A2Up0.0789421292
PubMed_21979375_A1Up0.1046237784
PubMed_21979375_A2Down-0.1264391223
GSE35957Up0.0567933565
GSE36640Up0.0481088581
GSE54402Up0.0058247804
GSE9593Up0.0360456038
GSE43922Up0.0178253044
GSE24585Up0.3155354842
GSE37065Down-0.0474633336
GSE28863_A1Down-0.0016713855
GSE28863_A2Up0.1276406944
GSE28863_A3Up0.1288685829
GSE28863_A4Up0.0238362297
GSE48662Up0.0702927723

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

L-Glutamic AcidDB00142 NUTR00027
4-(1-Amino-1-Carboxy-Ethyl)-Benzoic AcidDB04256 EXPT02133

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-124-3pMIMAT0000422MIRT022650MicroarrayFunctional MTI (Weak)18668037
Entries Per Page
Displaying Page of
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.