HCSGD entry for GRM1
1. General information
| Official gene symbol | GRM1 |
|---|---|
| Entrez ID | 2911 |
| Gene full name | glutamate receptor, metabotropic 1 |
| Other gene symbols | GPRC1A MGLU1 MGLUR1 SCAR13 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000186 | Activation of MAPKK activity | IEA | biological_process |
| GO:0000187 | Activation of MAPK activity | IEA | biological_process |
| GO:0004930 | G-protein coupled receptor activity | IEA TAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0005886 | Plasma membrane | IEA TAS | cellular_component |
| GO:0005887 | Integral component of plasma membrane | TAS | cellular_component |
| GO:0007186 | G-protein coupled receptor signaling pathway | TAS | biological_process |
| GO:0007268 | Synaptic transmission | TAS | biological_process |
| GO:0007626 | Locomotory behavior | IEA | biological_process |
| GO:0008066 | Glutamate receptor activity | IDA TAS | molecular_function |
| GO:0008219 | Cell death | IEA | biological_process |
| GO:0014069 | Postsynaptic density | IEA | cellular_component |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0019233 | Sensory perception of pain | IEA | biological_process |
| GO:0030425 | Dendrite | IEA | cellular_component |
| GO:0038038 | G-protein coupled receptor homodimeric complex | IPI | cellular_component |
| GO:0051930 | Regulation of sensory perception of pain | IEA | biological_process |
| GO:0071257 | Cellular response to electrical stimulus | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.5500714335 | 0.9532838684 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1625403726 |
| GSE13712_SHEAR | Up | 0.0060402110 |
| GSE13712_STATIC | Up | 0.0325087069 |
| GSE19018 | Up | 0.1984450440 |
| GSE19899_A1 | Up | 0.0132980237 |
| GSE19899_A2 | Up | 0.0789421292 |
| PubMed_21979375_A1 | Up | 0.1046237784 |
| PubMed_21979375_A2 | Down | -0.1264391223 |
| GSE35957 | Up | 0.0567933565 |
| GSE36640 | Up | 0.0481088581 |
| GSE54402 | Up | 0.0058247804 |
| GSE9593 | Up | 0.0360456038 |
| GSE43922 | Up | 0.0178253044 |
| GSE24585 | Up | 0.3155354842 |
| GSE37065 | Down | -0.0474633336 |
| GSE28863_A1 | Down | -0.0016713855 |
| GSE28863_A2 | Up | 0.1276406944 |
| GSE28863_A3 | Up | 0.1288685829 |
| GSE28863_A4 | Up | 0.0238362297 |
| GSE48662 | Up | 0.0702927723 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| L-Glutamic Acid | DB00142 | NUTR00027 |
| 4-(1-Amino-1-Carboxy-Ethyl)-Benzoic Acid | DB04256 | EXPT02133 |
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-124-3p | MIMAT0000422 | MIRT022650 | Microarray | Functional MTI (Weak) | 18668037 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
