HCSGD entry for LAMTOR2

1. General information

Official gene symbolLAMTOR2
Entrez ID28956
Gene full namelate endosomal/lysosomal adaptor, MAPK and MTOR activator 2
Other gene symbolsENDAP HSPC003 MAPBPIP MAPKSP1AP ROBLD3 Ragulator2 p14
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000186Activation of MAPKK activityIEAbiological_process
GO:0005085Guanyl-nucleotide exchange factor activityIDAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005765Lysosomal membraneIDAcellular_component
GO:0005770Late endosomeISScellular_component
GO:0016049Cell growthIMPbiological_process
GO:0032008Positive regulation of TOR signalingIMPbiological_process
GO:0032947Protein complex scaffoldIDAmolecular_function
GO:0034613Cellular protein localizationIMPbiological_process
GO:0043087Regulation of GTPase activityIDAbiological_process
GO:0071230Cellular response to amino acid stimulusIMPbiological_process
GO:0071986Ragulator complexIDAcellular_component
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.29740017100.51464233500.99655455701.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.4936451516
GSE13712_SHEARDown-0.0469606131
GSE13712_STATICUp0.0586953697
GSE19018Up0.0229280137
GSE19899_A1Up0.2504140529
GSE19899_A2Up0.1910738198
PubMed_21979375_A1Up0.5838849438
PubMed_21979375_A2Down-0.1812148583
GSE35957Down-0.3045665443
GSE36640Up0.3071396798
GSE54402Up0.1581047754
GSE9593Up0.0579037553
GSE43922Up0.1031005887
GSE24585Down-0.0746510120
GSE37065Down-0.0925181295
GSE28863_A1Down-0.2772320647
GSE28863_A2Down-0.1178750734
GSE28863_A3Down-0.3515854356
GSE28863_A4Down-0.1711678932
GSE48662Up0.2982640645

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-16-5pMIMAT0000069MIRT005438pSILAC//ProteomicsFunctional MTI (Weak)18668040
hsa-miR-615-3pMIMAT0003283MIRT040283CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.