HCSGD entry for GRIA1

1. General information

Official gene symbolGRIA1
Entrez ID2890
Gene full nameglutamate receptor, ionotropic, AMPA 1
Other gene symbolsGLUH1 GLUR1 GLURA GluA1 HBGR1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004971Alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activityIDAmolecular_function
GO:0005234Extracellular-glutamate-gated ion channel activityIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005789Endoplasmic reticulum membraneIEAcellular_component
GO:0005886Plasma membraneTAScellular_component
GO:0007165Signal transductionTASbiological_process
GO:0007268Synaptic transmissionTASbiological_process
GO:0007616Long-term memoryIEAbiological_process
GO:0008021Synaptic vesicleIEAcellular_component
GO:0008066Glutamate receptor activityTASmolecular_function
GO:0009986Cell surfaceISScellular_component
GO:0014069Postsynaptic densityISScellular_component
GO:0030054Cell junctionIEAcellular_component
GO:0030165PDZ domain bindingISSmolecular_function
GO:0030425DendriteISScellular_component
GO:0030666Endocytic vesicle membraneTAScellular_component
GO:0031623Receptor internalizationIEAbiological_process
GO:0032281Alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complexISScellular_component
GO:0032590Dendrite membraneIEAcellular_component
GO:0034220Ion transmembrane transportIDAbiological_process
GO:0035235Ionotropic glutamate receptor signaling pathwayIDAbiological_process
GO:0043025Neuronal cell bodyISScellular_component
GO:0043197Dendritic spineISScellular_component
GO:0044309Neuron spineISScellular_component
GO:0045211Postsynaptic membraneIEAcellular_component
GO:0055085Transmembrane transportIDAbiological_process
Entries Per Page
Displaying Page of

4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.13629104520.90189794460.74494221351.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1115204444
GSE13712_SHEARDown-0.0336818459
GSE13712_STATICUp0.0619282309
GSE19018Down-0.1346665411
GSE19899_A1Up0.0480103115
GSE19899_A2Up0.1104807576
PubMed_21979375_A1Down-0.0856331094
PubMed_21979375_A2Up0.1831024162
GSE35957Down-0.1896406262
GSE36640Down-0.0606947985
GSE54402Up0.0254622531
GSE9593Up0.0596305534
GSE43922Up0.0125365483
GSE24585Up0.0086469877
GSE37065Down-0.1374268489
GSE28863_A1Up0.8189431335
GSE28863_A2Up1.4400116135
GSE28863_A3Up0.3307048974
GSE28863_A4Up0.1098683024
GSE48662Down-0.1314595872

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

L-Glutamic AcidDB00142 NUTR00027
EnfluraneDB00228 APRD00234
IsofluraneDB00753 APRD00212
MethoxyfluraneDB01028 APRD00744
DesfluraneDB01189 APRD00907
SevofluraneDB01236 APRD00219
TalampanelDB04982 -
CX717DB05047 -
PerampanelDB08883 -

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-192-5pMIMAT0000222MIRT004156MicroarrayFunctional MTI (Weak)16822819
hsa-miR-335-5pMIMAT0000765MIRT018501MicroarrayFunctional MTI (Weak)18185580
Entries Per Page
Displaying Page of
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.