HCSGD entry for LIN9


1. General information

Official gene symbolLIN9
Entrez ID286826
Gene full namelin-9 homolog (C. elegans)
Other gene symbolsBARA BARPsv Lin-9 TGS TGS1 TGS2
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000278Mitotic cell cycleTASbiological_process
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005654NucleoplasmTAScellular_component
GO:0005730NucleolusIDAcellular_component
GO:0006260DNA replicationIEAbiological_process
GO:0006351Transcription, DNA-templatedIEAbiological_process
GO:0007049Cell cycleIEAbiological_process
GO:0017053Transcriptional repressor complexIEAcellular_component
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.91760666010.03611828580.99999024730.3581466717

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1611134378
GSE13712_SHEARDown-0.0113875897
GSE13712_STATICDown-0.1203611028
GSE19018Down-0.1285624498
GSE19899_A1Down-0.0563164765
GSE19899_A2Down-0.5665221038
PubMed_21979375_A1Up0.2588340311
PubMed_21979375_A2Down-0.6631488875
GSE35957Down-0.5445788282
GSE36640Down-0.8785046617
GSE54402Down-0.1028397082
GSE9593Down-0.1971973509
GSE43922Down-0.3741441519
GSE24585Up0.4053652487
GSE37065Down-0.0694194600
GSE28863_A1Down-0.1993297132
GSE28863_A2Up0.9675751729
GSE28863_A3Down-0.4972736802
GSE28863_A4Down-0.2048154636
GSE48662Up0.0398557434

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-215-5pMIMAT0000272MIRT024654MicroarrayFunctional MTI (Weak)19074876
hsa-miR-192-5pMIMAT0000222MIRT026672MicroarrayFunctional MTI (Weak)19074876
hsa-miR-30c-5pMIMAT0000244MIRT047967CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.


PubMed ID of the article

Sentenece the gene occurs

22366686Thus, we identify cellular senescence as the an endogenous signal of miRNA/AGO2-mediated TGS in human cells
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