HCSGD entry for LIN9
1. General information
| Official gene symbol | LIN9 |
|---|---|
| Entrez ID | 286826 |
| Gene full name | lin-9 homolog (C. elegans) |
| Other gene symbols | BARA BARPsv Lin-9 TGS TGS1 TGS2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000278 | Mitotic cell cycle | TAS | biological_process |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005654 | Nucleoplasm | TAS | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0006260 | DNA replication | IEA | biological_process |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0007049 | Cell cycle | IEA | biological_process |
| GO:0017053 | Transcriptional repressor complex | IEA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9176066601 | 0.0361182858 | 0.9999902473 | 0.3581466717 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1611134378 |
| GSE13712_SHEAR | Down | -0.0113875897 |
| GSE13712_STATIC | Down | -0.1203611028 |
| GSE19018 | Down | -0.1285624498 |
| GSE19899_A1 | Down | -0.0563164765 |
| GSE19899_A2 | Down | -0.5665221038 |
| PubMed_21979375_A1 | Up | 0.2588340311 |
| PubMed_21979375_A2 | Down | -0.6631488875 |
| GSE35957 | Down | -0.5445788282 |
| GSE36640 | Down | -0.8785046617 |
| GSE54402 | Down | -0.1028397082 |
| GSE9593 | Down | -0.1971973509 |
| GSE43922 | Down | -0.3741441519 |
| GSE24585 | Up | 0.4053652487 |
| GSE37065 | Down | -0.0694194600 |
| GSE28863_A1 | Down | -0.1993297132 |
| GSE28863_A2 | Up | 0.9675751729 |
| GSE28863_A3 | Down | -0.4972736802 |
| GSE28863_A4 | Down | -0.2048154636 |
| GSE48662 | Up | 0.0398557434 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-215-5p | MIMAT0000272 | MIRT024654 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-192-5p | MIMAT0000222 | MIRT026672 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-30c-5p | MIMAT0000244 | MIRT047967 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 22366686 | Thus, we identify cellular senescence as the an endogenous signal of miRNA/AGO2-mediated TGS in human cells |
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