HCSGD entry for RNF180


1. General information

Official gene symbolRNF180
Entrez ID285671
Gene full namering finger protein 180
Other gene symbols
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004842Ubiquitin-protein ligase activityIEAmolecular_function
GO:0005635Nuclear envelopeIEAcellular_component
GO:0008270Zinc ion bindingIEAmolecular_function
GO:0016021Integral component of membraneIEAcellular_component
GO:0031227Intrinsic component of endoplasmic reticulum membraneIEAcellular_component
GO:0031624Ubiquitin conjugating enzyme bindingIEAmolecular_function
GO:0032436Positive regulation of proteasomal ubiquitin-dependent protein catabolic processIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.43880666010.18882780670.99999024730.8422532961

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0137497474
GSE13712_SHEARDown-0.7016117767
GSE13712_STATICDown-0.1279664677
GSE19018Up0.0492532371
GSE19899_A1Up0.0332772732
GSE19899_A2Down-0.2480658570
PubMed_21979375_A1Up0.1058647194
PubMed_21979375_A2Up0.1159039830
GSE35957Down-0.1774646583
GSE36640Up0.0382412303
GSE54402Up0.0513627179
GSE9593Down-0.2460724023
GSE43922Up0.0231982866
GSE24585Up0.6633492910
GSE37065Down-0.2517788370
GSE28863_A1Down-0.2906205918
GSE28863_A2Down-0.2069717350
GSE28863_A3Up0.5899586857
GSE28863_A4Down-0.1147864834
GSE48662Up0.1041788638

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.