HCSGD entry for ANGPT2

1. General information

Official gene symbolANGPT2
Entrez ID285
Gene full nameangiopoietin 2
Other gene symbolsAGPT2 ANG2
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001525AngiogenesisIEAbiological_process
GO:0001666Response to hypoxiaIEAbiological_process
GO:0005102Receptor bindingTASmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005576Extracellular regionTAScellular_component
GO:0005615Extracellular spaceIDAcellular_component
GO:0005634NucleusIEAcellular_component
GO:0005886Plasma membraneIEAcellular_component
GO:0007165Signal transductionTASbiological_process
GO:0007281Germ cell developmentIEAbiological_process
GO:0007596Blood coagulationTASbiological_process
GO:0009314Response to radiationIEAbiological_process
GO:0009612Response to mechanical stimulusIEAbiological_process
GO:0009749Response to glucoseIEAbiological_process
GO:0010812Negative regulation of cell-substrate adhesionIEAbiological_process
GO:0014070Response to organic cyclic compoundIEAbiological_process
GO:0014823Response to activityIEAbiological_process
GO:0016525Negative regulation of angiogenesisIEAbiological_process
GO:0030971Receptor tyrosine kinase bindingIPImolecular_function
GO:0031100Organ regenerationIEAbiological_process
GO:0042995Cell projectionIEAcellular_component
GO:0043537Negative regulation of blood vessel endothelial cell migrationIDAbiological_process
GO:0045766Positive regulation of angiogenesisIEAbiological_process
GO:0046872Metal ion bindingIEAmolecular_function
GO:0048014Tie signaling pathwayIDAbiological_process
GO:0050900Leukocyte migrationTASbiological_process
GO:0050928Negative regulation of positive chemotaxisIDAbiological_process
GO:0060135Maternal process involved in female pregnancyIEAbiological_process
GO:0071363Cellular response to growth factor stimulusIEAbiological_process
GO:0072012Glomerulus vasculature developmentISSbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.00660131070.97858111010.21415073711.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1256841082
GSE13712_SHEARUp1.7658386961
GSE13712_STATICUp0.9008812537
GSE19018Up0.1008489149
GSE19899_A1Up0.1510390920
GSE19899_A2Up0.5242846772
PubMed_21979375_A1Up0.7929724498
PubMed_21979375_A2Up0.2254841455
GSE35957Up0.1773824271
GSE36640Up0.0888698786
GSE54402Up1.4333954883
GSE9593Down-0.2252610094
GSE43922Up1.0830143018
GSE24585Up0.3665087779
GSE37065Up0.1741229231
GSE28863_A1Up0.0693187988
GSE28863_A2Up0.0253936086
GSE28863_A3Down-0.1433531677
GSE28863_A4Up0.1050961241
GSE48662Down-0.0647501665

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.