HCSGD entry for ANGPT2

1. General information

Official gene symbolANGPT2
Entrez ID285
Gene full nameangiopoietin 2
Other gene symbolsAGPT2 ANG2
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001525AngiogenesisIEAbiological_process
GO:0001666Response to hypoxiaIEAbiological_process
GO:0005102Receptor bindingTASmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005576Extracellular regionTAScellular_component
GO:0005615Extracellular spaceIDAcellular_component
GO:0005634NucleusIEAcellular_component
GO:0005886Plasma membraneIEAcellular_component
GO:0007165Signal transductionTASbiological_process
GO:0007281Germ cell developmentIEAbiological_process
GO:0007596Blood coagulationTASbiological_process
GO:0009314Response to radiationIEAbiological_process
GO:0009612Response to mechanical stimulusIEAbiological_process
GO:0009749Response to glucoseIEAbiological_process
GO:0010812Negative regulation of cell-substrate adhesionIEAbiological_process
GO:0014070Response to organic cyclic compoundIEAbiological_process
GO:0014823Response to activityIEAbiological_process
GO:0016525Negative regulation of angiogenesisIEAbiological_process
GO:0030971Receptor tyrosine kinase bindingIPImolecular_function
GO:0031100Organ regenerationIEAbiological_process
GO:0042995Cell projectionIEAcellular_component
GO:0043537Negative regulation of blood vessel endothelial cell migrationIDAbiological_process
GO:0045766Positive regulation of angiogenesisIEAbiological_process
GO:0046872Metal ion bindingIEAmolecular_function
GO:0048014Tie signaling pathwayIDAbiological_process
GO:0050900Leukocyte migrationTASbiological_process
GO:0050928Negative regulation of positive chemotaxisIDAbiological_process
GO:0060135Maternal process involved in female pregnancyIEAbiological_process
GO:0071363Cellular response to growth factor stimulusIEAbiological_process
GO:0072012Glomerulus vasculature developmentISSbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.00660131070.97858111010.21415073711.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1256841082
GSE13712_SHEARUp1.7658386961
GSE13712_STATICUp0.9008812537
GSE19018Up0.1008489149
GSE19899_A1Up0.1510390920
GSE19899_A2Up0.5242846772
PubMed_21979375_A1Up0.7929724498
PubMed_21979375_A2Up0.2254841455
GSE35957Up0.1773824271
GSE36640Up0.0888698786
GSE54402Up1.4333954883
GSE9593Down-0.2252610094
GSE43922Up1.0830143018
GSE24585Up0.3665087779
GSE37065Up0.1741229231
GSE28863_A1Up0.0693187988
GSE28863_A2Up0.0253936086
GSE28863_A3Down-0.1433531677
GSE28863_A4Up0.1050961241
GSE48662Down-0.0647501665

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.