HCSGD entry for PROX2
1. General information
| Official gene symbol | PROX2 |
|---|---|
| Entrez ID | 283571 |
| Gene full name | prospero homeobox 2 |
| Other gene symbols | PROX-2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0006355 | Regulation of transcription, DNA-templated | IEA | biological_process |
| GO:0007275 | Multicellular organismal development | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7787910034 | 0.5420336575 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0127546409 |
| GSE13712_SHEAR | Up | 0.0721778084 |
| GSE13712_STATIC | Down | -0.1100492575 |
| GSE19018 | Up | 0.2003948108 |
| GSE19899_A1 | Down | -0.0406248250 |
| GSE19899_A2 | Up | 0.0889678471 |
| PubMed_21979375_A1 | Down | -0.1042636784 |
| PubMed_21979375_A2 | Down | -0.1256294311 |
| GSE35957 | Down | -0.0261229163 |
| GSE36640 | Up | 0.3696983534 |
| GSE54402 | Up | 0.0062535238 |
| GSE9593 | Down | -0.0169577217 |
| GSE43922 | Up | 0.0178024889 |
| GSE24585 | Up | 0.1085307072 |
| GSE37065 | Down | -0.0828708899 |
| GSE28863_A1 | Down | -0.1749360568 |
| GSE28863_A2 | Down | -0.3597341156 |
| GSE28863_A3 | Down | -0.0837304768 |
| GSE28863_A4 | Up | 0.0559573243 |
| GSE48662 | Up | 0.1086094376 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT018506 | Microarray | Functional MTI (Weak) | 18185580 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
