HCSGD entry for PROX2


1. General information

Official gene symbolPROX2
Entrez ID283571
Gene full nameprospero homeobox 2
Other gene symbolsPROX-2
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003677DNA bindingIEAmolecular_function
GO:0005634NucleusIEAcellular_component
GO:0006351Transcription, DNA-templatedIEAbiological_process
GO:0006355Regulation of transcription, DNA-templatedIEAbiological_process
GO:0007275Multicellular organismal developmentIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.77879100340.54203365750.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0127546409
GSE13712_SHEARUp0.0721778084
GSE13712_STATICDown-0.1100492575
GSE19018Up0.2003948108
GSE19899_A1Down-0.0406248250
GSE19899_A2Up0.0889678471
PubMed_21979375_A1Down-0.1042636784
PubMed_21979375_A2Down-0.1256294311
GSE35957Down-0.0261229163
GSE36640Up0.3696983534
GSE54402Up0.0062535238
GSE9593Down-0.0169577217
GSE43922Up0.0178024889
GSE24585Up0.1085307072
GSE37065Down-0.0828708899
GSE28863_A1Down-0.1749360568
GSE28863_A2Down-0.3597341156
GSE28863_A3Down-0.0837304768
GSE28863_A4Up0.0559573243
GSE48662Up0.1086094376

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT018506MicroarrayFunctional MTI (Weak)18185580
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.