HCSGD entry for MKX
1. General information
| Official gene symbol | MKX |
|---|---|
| Entrez ID | 283078 |
| Gene full name | mohawk homeobox |
| Other gene symbols | C10orf48 IFRX IRXL1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000122 | Negative regulation of transcription from RNA polymerase II promoter | IEA | biological_process |
| GO:0000981 | Sequence-specific DNA binding RNA polymerase II transcription factor activity | IEA | molecular_function |
| GO:0001085 | RNA polymerase II transcription factor binding | IEA | molecular_function |
| GO:0002932 | Tendon sheath development | IEA | biological_process |
| GO:0003700 | Sequence-specific DNA binding transcription factor activity | IEA | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0007517 | Muscle organ development | IEA ISS | biological_process |
| GO:0010628 | Positive regulation of gene expression | IEA | biological_process |
| GO:0030199 | Collagen fibril organization | IEA | biological_process |
| GO:0032967 | Positive regulation of collagen biosynthetic process | IEA | biological_process |
| GO:0035990 | Tendon cell differentiation | IEA | biological_process |
| GO:0043565 | Sequence-specific DNA binding | IEA | molecular_function |
| GO:0045662 | Negative regulation of myoblast differentiation | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7103616922 | 0.1954290225 | 0.9999902473 | 0.8566007161 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0000646100 |
| GSE13712_SHEAR | Up | 0.1499312423 |
| GSE13712_STATIC | Up | 0.0395466813 |
| GSE19018 | Down | -0.3527118908 |
| GSE19899_A1 | Up | 0.0634900501 |
| GSE19899_A2 | Down | -0.2826100778 |
| PubMed_21979375_A1 | Down | -0.0102952844 |
| PubMed_21979375_A2 | Down | -0.0134329171 |
| GSE35957 | Up | 1.3551548267 |
| GSE36640 | Down | -0.2700677719 |
| GSE54402 | Down | -1.0207530045 |
| GSE9593 | Up | 0.0298393154 |
| GSE43922 | Up | 0.0215460641 |
| GSE24585 | Down | -0.1048122424 |
| GSE37065 | Up | 0.1900308829 |
| GSE28863_A1 | Up | 0.0472268421 |
| GSE28863_A2 | Down | -0.1785686939 |
| GSE28863_A3 | Down | -0.1591423680 |
| GSE28863_A4 | Up | 0.0075752062 |
| GSE48662 | Down | -0.0649123086 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-148b-3p | MIMAT0000759 | MIRT019321 | Microarray | Functional MTI (Weak) | 17612493 |
| hsa-miR-124-3p | MIMAT0000422 | MIRT022766 | Microarray | Functional MTI (Weak) | 18668037 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
