HCSGD entry for MKX

1. General information

Official gene symbolMKX
Entrez ID283078
Gene full namemohawk homeobox
Other gene symbolsC10orf48 IFRX IRXL1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000122Negative regulation of transcription from RNA polymerase II promoterIEAbiological_process
GO:0000981Sequence-specific DNA binding RNA polymerase II transcription factor activityIEAmolecular_function
GO:0001085RNA polymerase II transcription factor bindingIEAmolecular_function
GO:0002932Tendon sheath developmentIEAbiological_process
GO:0003700Sequence-specific DNA binding transcription factor activityIEAmolecular_function
GO:0005634NucleusIEAcellular_component
GO:0007517Muscle organ developmentIEA ISSbiological_process
GO:0010628Positive regulation of gene expressionIEAbiological_process
GO:0030199Collagen fibril organizationIEAbiological_process
GO:0032967Positive regulation of collagen biosynthetic processIEAbiological_process
GO:0035990Tendon cell differentiationIEAbiological_process
GO:0043565Sequence-specific DNA bindingIEAmolecular_function
GO:0045662Negative regulation of myoblast differentiationIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.71036169220.19542902250.99999024730.8566007161

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0000646100
GSE13712_SHEARUp0.1499312423
GSE13712_STATICUp0.0395466813
GSE19018Down-0.3527118908
GSE19899_A1Up0.0634900501
GSE19899_A2Down-0.2826100778
PubMed_21979375_A1Down-0.0102952844
PubMed_21979375_A2Down-0.0134329171
GSE35957Up1.3551548267
GSE36640Down-0.2700677719
GSE54402Down-1.0207530045
GSE9593Up0.0298393154
GSE43922Up0.0215460641
GSE24585Down-0.1048122424
GSE37065Up0.1900308829
GSE28863_A1Up0.0472268421
GSE28863_A2Down-0.1785686939
GSE28863_A3Down-0.1591423680
GSE28863_A4Up0.0075752062
GSE48662Down-0.0649123086

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-148b-3pMIMAT0000759MIRT019321MicroarrayFunctional MTI (Weak)17612493
hsa-miR-124-3pMIMAT0000422MIRT022766MicroarrayFunctional MTI (Weak)18668037
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.