HCSGD entry for GNA11

1. General information

Official gene symbolGNA11
Entrez ID2767
Gene full nameguanine nucleotide binding protein (G protein), alpha 11 (Gq class)
Other gene symbolsGNA-11
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001501Skeletal system developmentIEAbiological_process
GO:0001508Action potentialIBAbiological_process
GO:0001664G-protein coupled receptor bindingIBA IEAmolecular_function
GO:0003924GTPase activityIEAmolecular_function
GO:0004871Signal transducer activityIBA IEAmolecular_function
GO:0005525GTP bindingIEAmolecular_function
GO:0005737CytoplasmTAScellular_component
GO:0005765Lysosomal membraneIDAcellular_component
GO:0005834Heterotrimeric G-protein complexIBAcellular_component
GO:0005886Plasma membraneTAScellular_component
GO:0007165Signal transductionTASbiological_process
GO:0007186G-protein coupled receptor signaling pathwayIEAbiological_process
GO:0007188Adenylate cyclase-modulating G-protein coupled receptor signaling pathwayIBAbiological_process
GO:0007507Heart developmentIEAbiological_process
GO:0007596Blood coagulationTASbiological_process
GO:0030168Platelet activationTASbiological_process
GO:0031234Extrinsic component of cytoplasmic side of plasma membraneIBAcellular_component
GO:0031683G-protein beta/gamma-subunit complex bindingIBA IEAmolecular_function
GO:0045634Regulation of melanocyte differentiationIEAbiological_process
GO:0046872Metal ion bindingIEAmolecular_function
GO:0048066Developmental pigmentationIEAbiological_process
GO:0060158Phospholipase C-activating dopamine receptor signaling pathwayIBAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.40128808940.69546942370.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1478346313
GSE13712_SHEARUp0.1402552112
GSE13712_STATICUp0.1079855740
GSE19018Up0.0782377833
GSE19899_A1Down-0.2685764823
GSE19899_A2Up0.5441264979
PubMed_21979375_A1Up0.1525485136
PubMed_21979375_A2Up0.4685336197
GSE35957Down-0.3751065858
GSE36640Up0.0616200528
GSE54402Up0.2378987393
GSE9593Up0.1679840858
GSE43922Down-0.0575580550
GSE24585Down-0.1908063788
GSE37065Down-0.2322308966
GSE28863_A1Up0.0546758143
GSE28863_A2Up0.0731073947
GSE28863_A3Up0.1743100805
GSE28863_A4Down-0.0307812689
GSE48662Down-0.0865050785

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.