HCSGD entry for GLUD2


1. General information

Official gene symbolGLUD2
Entrez ID2747
Gene full nameglutamate dehydrogenase 2
Other gene symbolsGDH2 GLUDP1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004352Glutamate dehydrogenase (NAD+) activityIDAmolecular_function
GO:0004353Glutamate dehydrogenase [NAD(P)+] activityIDAmolecular_function
GO:0005525GTP bindingIDAmolecular_function
GO:0005737CytoplasmIDAcellular_component
GO:0005739MitochondrionIDAcellular_component
GO:0006536Glutamate metabolic processIDAbiological_process
GO:0006537Glutamate biosynthetic processIDAbiological_process
GO:0006538Glutamate catabolic processIDAbiological_process
GO:0043531ADP bindingIDAmolecular_function
GO:0055114Oxidation-reduction processIDAbiological_process
GO:0070728Leucine bindingIDAmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.80089312720.56520795180.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1082031364
GSE13712_SHEARUp0.0779047950
GSE13712_STATICUp0.0632257472
GSE19018Down-0.0276520747
GSE19899_A1Up0.0589555527
GSE19899_A2Down-0.2191174122
PubMed_21979375_A1Up0.0106508926
PubMed_21979375_A2Down-0.4379720433
GSE35957Down-0.0073320487
GSE36640Up0.1227364824
GSE54402Down-0.0483408732
GSE9593Up0.2275130385
GSE43922Up0.0179614895
GSE24585Down-0.0774200247
GSE37065Down-0.0174704227
GSE28863_A1--
GSE28863_A2--
GSE28863_A3--
GSE28863_A4--
GSE48662Down-0.2495841084

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

L-Glutamic AcidDB00142 NUTR00027
NADHDB00157 NUTR00041 | DB01907 | EXPT02287 | DB03527

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-1226-3pMIMAT0005577MIRT036419CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.