HCSGD entry for GLUD2
1. General information
| Official gene symbol | GLUD2 |
|---|---|
| Entrez ID | 2747 |
| Gene full name | glutamate dehydrogenase 2 |
| Other gene symbols | GDH2 GLUDP1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004352 | Glutamate dehydrogenase (NAD+) activity | IDA | molecular_function |
| GO:0004353 | Glutamate dehydrogenase [NAD(P)+] activity | IDA | molecular_function |
| GO:0005525 | GTP binding | IDA | molecular_function |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005739 | Mitochondrion | IDA | cellular_component |
| GO:0006536 | Glutamate metabolic process | IDA | biological_process |
| GO:0006537 | Glutamate biosynthetic process | IDA | biological_process |
| GO:0006538 | Glutamate catabolic process | IDA | biological_process |
| GO:0043531 | ADP binding | IDA | molecular_function |
| GO:0055114 | Oxidation-reduction process | IDA | biological_process |
| GO:0070728 | Leucine binding | IDA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8008931272 | 0.5652079518 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1082031364 |
| GSE13712_SHEAR | Up | 0.0779047950 |
| GSE13712_STATIC | Up | 0.0632257472 |
| GSE19018 | Down | -0.0276520747 |
| GSE19899_A1 | Up | 0.0589555527 |
| GSE19899_A2 | Down | -0.2191174122 |
| PubMed_21979375_A1 | Up | 0.0106508926 |
| PubMed_21979375_A2 | Down | -0.4379720433 |
| GSE35957 | Down | -0.0073320487 |
| GSE36640 | Up | 0.1227364824 |
| GSE54402 | Down | -0.0483408732 |
| GSE9593 | Up | 0.2275130385 |
| GSE43922 | Up | 0.0179614895 |
| GSE24585 | Down | -0.0774200247 |
| GSE37065 | Down | -0.0174704227 |
| GSE28863_A1 | - | - |
| GSE28863_A2 | - | - |
| GSE28863_A3 | - | - |
| GSE28863_A4 | - | - |
| GSE48662 | Down | -0.2495841084 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| L-Glutamic Acid | DB00142 | NUTR00027 |
| NADH | DB00157 | NUTR00041 | DB01907 | EXPT02287 | DB03527 |
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-1226-3p | MIMAT0005577 | MIRT036419 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
