HCSGD entry for GLP1R

1. General information

Official gene symbolGLP1R
Entrez ID2740
Gene full nameglucagon-like peptide 1 receptor
Other gene symbols
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004888Transmembrane signaling receptor activityTASmolecular_function
GO:0004967Glucagon receptor activityIEAmolecular_function
GO:0005886Plasma membraneTAScellular_component
GO:0006112Energy reserve metabolic processTASbiological_process
GO:0007190Activation of adenylate cyclase activityTASbiological_process
GO:0007204Positive regulation of cytosolic calcium ion concentrationIDAbiological_process
GO:0016021Integral component of membraneIEAcellular_component
GO:0019933CAMP-mediated signalingIDAbiological_process
GO:0044281Small molecule metabolic processTASbiological_process
GO:0050796Regulation of insulin secretionTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.59786933630.93623840280.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0077203084
GSE13712_SHEARDown-0.1577595554
GSE13712_STATICDown-0.0653095070
GSE19018Up0.1440894695
GSE19899_A1Up0.0539329115
GSE19899_A2Up0.0627469348
PubMed_21979375_A1Up0.1528604276
PubMed_21979375_A2Up0.0783547706
GSE35957Up0.1808990666
GSE36640Up0.0493162935
GSE54402Up0.0697880320
GSE9593Down-0.0449425028
GSE43922Up0.0521773723
GSE24585Up0.0614388949
GSE37065Up0.0614939909
GSE28863_A1Up0.0070997487
GSE28863_A2Up0.0029166995
GSE28863_A3Up0.2052833620
GSE28863_A4Up0.0677886767
GSE48662Up0.0033403392

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

Glucagon recombinantDB00040 BTD00057 | BIOD00057
ExenatideDB01276 -
GSK716155DB05162 -
AlbiglutideDB09043 -
DulaglutideDB09045 -

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.