HCSGD entry for GLP1R
1. General information
| Official gene symbol | GLP1R |
|---|---|
| Entrez ID | 2740 |
| Gene full name | glucagon-like peptide 1 receptor |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004888 | Transmembrane signaling receptor activity | TAS | molecular_function |
| GO:0004967 | Glucagon receptor activity | IEA | molecular_function |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0006112 | Energy reserve metabolic process | TAS | biological_process |
| GO:0007190 | Activation of adenylate cyclase activity | TAS | biological_process |
| GO:0007204 | Positive regulation of cytosolic calcium ion concentration | IDA | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0019933 | CAMP-mediated signaling | IDA | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0050796 | Regulation of insulin secretion | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.5978693363 | 0.9362384028 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0077203084 |
| GSE13712_SHEAR | Down | -0.1577595554 |
| GSE13712_STATIC | Down | -0.0653095070 |
| GSE19018 | Up | 0.1440894695 |
| GSE19899_A1 | Up | 0.0539329115 |
| GSE19899_A2 | Up | 0.0627469348 |
| PubMed_21979375_A1 | Up | 0.1528604276 |
| PubMed_21979375_A2 | Up | 0.0783547706 |
| GSE35957 | Up | 0.1808990666 |
| GSE36640 | Up | 0.0493162935 |
| GSE54402 | Up | 0.0697880320 |
| GSE9593 | Down | -0.0449425028 |
| GSE43922 | Up | 0.0521773723 |
| GSE24585 | Up | 0.0614388949 |
| GSE37065 | Up | 0.0614939909 |
| GSE28863_A1 | Up | 0.0070997487 |
| GSE28863_A2 | Up | 0.0029166995 |
| GSE28863_A3 | Up | 0.2052833620 |
| GSE28863_A4 | Up | 0.0677886767 |
| GSE48662 | Up | 0.0033403392 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| Glucagon recombinant | DB00040 | BTD00057 | BIOD00057 |
| Exenatide | DB01276 | - |
| GSK716155 | DB05162 | - |
| Albiglutide | DB09043 | - |
| Dulaglutide | DB09045 | - |

