HCSGD entry for HSPB7
1. General information
| Official gene symbol | HSPB7 |
|---|---|
| Entrez ID | 27129 |
| Gene full name | heat shock 27kDa protein family, member 7 (cardiovascular) |
| Other gene symbols | cvHSP |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005739 | Mitochondrion | IEA | cellular_component |
| GO:0006950 | Response to stress | IEA | biological_process |
| GO:0006986 | Response to unfolded protein | TAS | biological_process |
| GO:0008016 | Regulation of heart contraction | TAS | biological_process |
| GO:0008022 | Protein C-terminus binding | TAS | molecular_function |
| GO:0015030 | Cajal body | IEA | cellular_component |
| GO:0015629 | Actin cytoskeleton | IEA | cellular_component |
| GO:0031005 | Filamin binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9206949736 | 0.0563907450 | 0.9999902473 | 0.4463920697 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.5165616380 |
| GSE13712_SHEAR | Up | 0.1063041359 |
| GSE13712_STATIC | Up | 0.0324412445 |
| GSE19018 | Down | -0.1262084434 |
| GSE19899_A1 | Up | 0.0327364534 |
| GSE19899_A2 | Up | 0.0413427123 |
| PubMed_21979375_A1 | Up | 0.0508347700 |
| PubMed_21979375_A2 | Down | -0.1266920351 |
| GSE35957 | Up | 0.6580422589 |
| GSE36640 | Up | 0.0558626487 |
| GSE54402 | Down | -0.1588076333 |
| GSE9593 | Down | -0.0361138831 |
| GSE43922 | Up | 0.0058456729 |
| GSE24585 | Up | 0.0456605856 |
| GSE37065 | Down | -0.0662733679 |
| GSE28863_A1 | Down | -0.5358989081 |
| GSE28863_A2 | Down | -0.4210667914 |
| GSE28863_A3 | Up | 0.0496230656 |
| GSE28863_A4 | Down | -0.3002277149 |
| GSE48662 | Down | -0.3116788660 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-124-3p | MIMAT0000422 | MIRT022635 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-98-5p | MIMAT0000096 | MIRT027658 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029397 | Microarray | Functional MTI (Weak) | 19088304 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
