HCSGD entry for HSPB7


1. General information

Official gene symbolHSPB7
Entrez ID27129
Gene full nameheat shock 27kDa protein family, member 7 (cardiovascular)
Other gene symbolscvHSP
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005737CytoplasmIDAcellular_component
GO:0005739MitochondrionIEAcellular_component
GO:0006950Response to stressIEAbiological_process
GO:0006986Response to unfolded proteinTASbiological_process
GO:0008016Regulation of heart contractionTASbiological_process
GO:0008022Protein C-terminus bindingTASmolecular_function
GO:0015030Cajal bodyIEAcellular_component
GO:0015629Actin cytoskeletonIEAcellular_component
GO:0031005Filamin bindingIEAmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.92069497360.05639074500.99999024730.4463920697

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.5165616380
GSE13712_SHEARUp0.1063041359
GSE13712_STATICUp0.0324412445
GSE19018Down-0.1262084434
GSE19899_A1Up0.0327364534
GSE19899_A2Up0.0413427123
PubMed_21979375_A1Up0.0508347700
PubMed_21979375_A2Down-0.1266920351
GSE35957Up0.6580422589
GSE36640Up0.0558626487
GSE54402Down-0.1588076333
GSE9593Down-0.0361138831
GSE43922Up0.0058456729
GSE24585Up0.0456605856
GSE37065Down-0.0662733679
GSE28863_A1Down-0.5358989081
GSE28863_A2Down-0.4210667914
GSE28863_A3Up0.0496230656
GSE28863_A4Down-0.3002277149
GSE48662Down-0.3116788660

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-124-3pMIMAT0000422MIRT022635MicroarrayFunctional MTI (Weak)18668037
hsa-miR-98-5pMIMAT0000096MIRT027658MicroarrayFunctional MTI (Weak)19088304
hsa-miR-26b-5pMIMAT0000083MIRT029397MicroarrayFunctional MTI (Weak)19088304
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.