HCSGD entry for LAT

1. General information

Official gene symbolLAT
Entrez ID27040
Gene full namelinker for activation of T cells
Other gene symbolsLAT1 pp36
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001772Immunological synapseIDA IEAcellular_component
GO:0005070SH3/SH2 adaptor activityIDAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005886Plasma membraneTAScellular_component
GO:0006954Inflammatory responseIEAbiological_process
GO:0006955Immune responseIDAbiological_process
GO:0007165Signal transductionIEAbiological_process
GO:0007229Integrin-mediated signaling pathwayIDAbiological_process
GO:0007265Ras protein signal transductionIMPbiological_process
GO:0007596Blood coagulationTASbiological_process
GO:0008180COP9 signalosomeIEA ISScellular_component
GO:0009967Positive regulation of signal transductionIDAbiological_process
GO:0010467Gene expressionIEAbiological_process
GO:0016020MembraneIEAcellular_component
GO:0016021Integral component of membraneIDAcellular_component
GO:0019722Calcium-mediated signalingIMPbiological_process
GO:0019901Protein kinase bindingIPImolecular_function
GO:0030168Platelet activationTASbiological_process
GO:0035556Intracellular signal transductionIDAbiological_process
GO:0038095Fc-epsilon receptor signaling pathwayTASbiological_process
GO:0042110T cell activationTASbiological_process
GO:0042629Mast cell granuleIEAcellular_component
GO:0043303Mast cell degranulationIEAbiological_process
GO:0045087Innate immune responseTASbiological_process
GO:0045121Membrane raftTAScellular_component
GO:0050852T cell receptor signaling pathwayTASbiological_process
GO:0050863Regulation of T cell activationIMPbiological_process
Entries Per Page
Displaying Page of

4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.07206219370.97796133130.57178409161.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1117323141
GSE13712_SHEARUp0.3170419054
GSE13712_STATICUp0.1856445392
GSE19018Up0.1025544712
GSE19899_A1Up0.0866508124
GSE19899_A2Up0.3573615501
PubMed_21979375_A1Up0.9706731662
PubMed_21979375_A2Up0.6612414400
GSE35957Down-0.0491943478
GSE36640Up1.0366599194
GSE54402Down-0.1455552130
GSE9593Down-0.0607464068
GSE43922Up0.3550289850
GSE24585Down-0.1109086415
GSE37065Down-0.0436759953
GSE28863_A1--
GSE28863_A2--
GSE28863_A3--
GSE28863_A4--
GSE48662Up0.1441762205

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.