HCSGD entry for TRMT2A


1. General information

Official gene symbolTRMT2A
Entrez ID27037
Gene full nametRNA methyltransferase 2 homolog A (S. cerevisiae)
Other gene symbolsHTF9C
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000166Nucleotide bindingIEAmolecular_function
GO:0003676Nucleic acid bindingIEAmolecular_function
GO:0003723RNA bindingIEAmolecular_function
GO:0006396RNA processingIEAbiological_process
GO:0008173RNA methyltransferase activityIEAmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.03766108050.95120245050.43823045981.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.2261094724
GSE13712_SHEARDown-0.2622978737
GSE13712_STATICDown-0.0998560475
GSE19018Up0.0279645866
GSE19899_A1Down-0.0241010422
GSE19899_A2Up0.6239129899
PubMed_21979375_A1Up1.7541860163
PubMed_21979375_A2Up1.2731817409
GSE35957Up0.0367924206
GSE36640Up0.1544729366
GSE54402Up0.2995768919
GSE9593Down-0.1551589939
GSE43922Up0.3106779104
GSE24585Down-0.1034142105
GSE37065Down-0.2063659460
GSE28863_A1Up0.0411347212
GSE28863_A2Down-0.0204358497
GSE28863_A3Up0.3326191261
GSE28863_A4Up0.1185446039
GSE48662Up0.4474073560

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-26b-5pMIMAT0000083MIRT029799MicroarrayFunctional MTI (Weak)19088304
hsa-miR-744-5pMIMAT0004945MIRT037605CLASHFunctional MTI (Weak)23622248
hsa-miR-193b-3pMIMAT0002819MIRT041422CLASHFunctional MTI (Weak)23622248
hsa-miR-125a-5pMIMAT0000443MIRT045766CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.