HCSGD entry for TRMT2A


1. General information

Official gene symbolTRMT2A
Entrez ID27037
Gene full nametRNA methyltransferase 2 homolog A (S. cerevisiae)
Other gene symbolsHTF9C
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000166Nucleotide bindingIEAmolecular_function
GO:0003676Nucleic acid bindingIEAmolecular_function
GO:0003723RNA bindingIEAmolecular_function
GO:0006396RNA processingIEAbiological_process
GO:0008173RNA methyltransferase activityIEAmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.03766108050.95120245050.43823045981.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.2261094724
GSE13712_SHEARDown-0.2622978737
GSE13712_STATICDown-0.0998560475
GSE19018Up0.0279645866
GSE19899_A1Down-0.0241010422
GSE19899_A2Up0.6239129899
PubMed_21979375_A1Up1.7541860163
PubMed_21979375_A2Up1.2731817409
GSE35957Up0.0367924206
GSE36640Up0.1544729366
GSE54402Up0.2995768919
GSE9593Down-0.1551589939
GSE43922Up0.3106779104
GSE24585Down-0.1034142105
GSE37065Down-0.2063659460
GSE28863_A1Up0.0411347212
GSE28863_A2Down-0.0204358497
GSE28863_A3Up0.3326191261
GSE28863_A4Up0.1185446039
GSE48662Up0.4474073560

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-26b-5pMIMAT0000083MIRT029799MicroarrayFunctional MTI (Weak)19088304
hsa-miR-744-5pMIMAT0004945MIRT037605CLASHFunctional MTI (Weak)23622248
hsa-miR-193b-3pMIMAT0002819MIRT041422CLASHFunctional MTI (Weak)23622248
hsa-miR-125a-5pMIMAT0000443MIRT045766CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.