HCSGD entry for B4GALT1

1. General information

Official gene symbolB4GALT1
Entrez ID2683
Gene full nameUDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
Other gene symbolsB4GAL-T1 CDG2D GGTB2 GT1 GTB beta4Gal-T1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000138Golgi trans cisternaIDAcellular_component
GO:0000139Golgi membraneTAScellular_component
GO:0002064Epithelial cell developmentIEAbiological_process
GO:0002526Acute inflammatory responseIEAbiological_process
GO:0003831Beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activityIDAmolecular_function
GO:0003945N-acetyllactosamine synthase activityIDAmolecular_function
GO:0004461Lactose synthase activityIDAmolecular_function
GO:0005576Extracellular regionIEAcellular_component
GO:0005794Golgi apparatusIDA IEAcellular_component
GO:0005886Plasma membraneIEA TAScellular_component
GO:0005975Carbohydrate metabolic processIEA TASbiological_process
GO:0005989Lactose biosynthetic processIEAbiological_process
GO:0006012Galactose metabolic processIEAbiological_process
GO:0006487Protein N-linked glycosylationIDAbiological_process
GO:0007155Cell adhesionIEAbiological_process
GO:0007219Notch signaling pathwayTASbiological_process
GO:0007338Single fertilizationTASbiological_process
GO:0007339Binding of sperm to zona pellucidaIEA TASbiological_process
GO:0007341Penetration of zona pellucidaIEAbiological_process
GO:0008092Cytoskeletal protein bindingIEAmolecular_function
GO:0008285Negative regulation of cell proliferationIEAbiological_process
GO:0008378Galactosyltransferase activityIEA NASmolecular_function
GO:0009101Glycoprotein biosynthetic processIEAbiological_process
GO:0009312Oligosaccharide biosynthetic processIDA NASbiological_process
GO:0009897External side of plasma membraneIDAcellular_component
GO:0009986Cell surfaceIEAcellular_component
GO:0016021Integral component of membraneIEAcellular_component
GO:0016323Basolateral plasma membraneIDAcellular_component
GO:0016757Transferase activity, transferring glycosyl groupsIEAmolecular_function
GO:0018146Keratan sulfate biosynthetic processTASbiological_process
GO:0018279Protein N-linked glycosylation via asparagineTASbiological_process
GO:0030057DesmosomeIDAcellular_component
GO:0030112GlycocalyxIDAcellular_component
GO:0030145Manganese ion bindingIDAmolecular_function
GO:0030198Extracellular matrix organizationIEAbiological_process
GO:0030203Glycosaminoglycan metabolic processTASbiological_process
GO:0030879Mammary gland developmentIEAbiological_process
GO:0031526Brush border membraneIDAcellular_component
GO:0032504Multicellular organism reproductionTASbiological_process
GO:0032580Golgi cisterna membraneIEAcellular_component
GO:0035250UDP-galactosyltransferase activityIDAmolecular_function
GO:0042339Keratan sulfate metabolic processTASbiological_process
GO:0042803Protein homodimerization activityIDAmolecular_function
GO:0043014Alpha-tubulin bindingIDAmolecular_function
GO:0043687Post-translational protein modificationTASbiological_process
GO:0044267Cellular protein metabolic processTASbiological_process
GO:0044281Small molecule metabolic processTASbiological_process
GO:0045136Development of secondary sexual characteristicsIEAbiological_process
GO:0048487Beta-tubulin bindingIPImolecular_function
GO:0048754Branching morphogenesis of an epithelial tubeIEAbiological_process
GO:0050900Leukocyte migrationIEAbiological_process
GO:0051270Regulation of cellular component movementIEAbiological_process
GO:0060046Regulation of acrosome reactionIEAbiological_process
GO:0060054Positive regulation of epithelial cell proliferation involved in wound healingIEAbiological_process
GO:0060055Angiogenesis involved in wound healingIEAbiological_process
GO:0060058Positive regulation of apoptotic process involved in mammary gland involutionIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.15667201470.54108726490.78577822031.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.4092006276
GSE13712_SHEARDown-0.1308369563
GSE13712_STATICDown-0.6376721278
GSE19018Up0.0048341439
GSE19899_A1Up0.0267032750
GSE19899_A2Up0.4216330031
PubMed_21979375_A1Up0.4659777066
PubMed_21979375_A2Up0.0947911156
GSE35957Up0.8898093385
GSE36640Down-0.0118824604
GSE54402Down-0.2855206066
GSE9593Down-0.1157483289
GSE43922Up0.5252152681
GSE24585Up0.0796398878
GSE37065Up0.1380352924
GSE28863_A1Up0.7138710453
GSE28863_A2Down-0.0069392950
GSE28863_A3Up0.1268363468
GSE28863_A4Down-0.0482878963
GSE48662Down-0.0176540716

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

N-Acetyl-D-glucosamineDB00141 NUTR00040
6-Aminohexyl-Uridine-C1,5'-DiphosphateDB02696 EXPT03171
Di(N-Acetyl-D-Glucosamine)DB03013 EXPT00851
Uridine-5'-MonophosphateDB03685 EXPT03155
2-(N-Morpholino)-Ethanesulfonic AcidDB03814 EXPT02154

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-124-3pMIMAT0000422MIRT002675MicroarrayFunctional MTI (Weak)15685193
hsa-miR-124-3pMIMAT0000422MIRT002675MicroarrayFunctional MTI (Weak)18668037
hsa-miR-155-5pMIMAT0000646MIRT020817ProteomicsFunctional MTI (Weak)18668040
hsa-miR-128-3pMIMAT0000424MIRT021980MicroarrayFunctional MTI (Weak)17612493
hsa-miR-122-5pMIMAT0000421MIRT023282MicroarrayFunctional MTI (Weak)17612493
hsa-miR-1MIMAT0000416MIRT023802ProteomicsFunctional MTI (Weak)18668040
hsa-miR-16-5pMIMAT0000069MIRT031774ProteomicsFunctional MTI (Weak)18668040
hsa-miR-484MIMAT0002174MIRT042255CLASHFunctional MTI (Weak)23622248
hsa-miR-15b-5pMIMAT0000417MIRT046468CLASHFunctional MTI (Weak)23622248
hsa-miR-18a-5pMIMAT0000072MIRT050738CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.