HCSGD entry for B4GALT1

1. General information

Official gene symbolB4GALT1
Entrez ID2683
Gene full nameUDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
Other gene symbolsB4GAL-T1 CDG2D GGTB2 GT1 GTB beta4Gal-T1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000138Golgi trans cisternaIDAcellular_component
GO:0000139Golgi membraneTAScellular_component
GO:0002064Epithelial cell developmentIEAbiological_process
GO:0002526Acute inflammatory responseIEAbiological_process
GO:0003831Beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activityIDAmolecular_function
GO:0003945N-acetyllactosamine synthase activityIDAmolecular_function
GO:0004461Lactose synthase activityIDAmolecular_function
GO:0005576Extracellular regionIEAcellular_component
GO:0005794Golgi apparatusIDA IEAcellular_component
GO:0005886Plasma membraneIEA TAScellular_component
GO:0005975Carbohydrate metabolic processIEA TASbiological_process
GO:0005989Lactose biosynthetic processIEAbiological_process
GO:0006012Galactose metabolic processIEAbiological_process
GO:0006487Protein N-linked glycosylationIDAbiological_process
GO:0007155Cell adhesionIEAbiological_process
GO:0007219Notch signaling pathwayTASbiological_process
GO:0007338Single fertilizationTASbiological_process
GO:0007339Binding of sperm to zona pellucidaIEA TASbiological_process
GO:0007341Penetration of zona pellucidaIEAbiological_process
GO:0008092Cytoskeletal protein bindingIEAmolecular_function
GO:0008285Negative regulation of cell proliferationIEAbiological_process
GO:0008378Galactosyltransferase activityIEA NASmolecular_function
GO:0009101Glycoprotein biosynthetic processIEAbiological_process
GO:0009312Oligosaccharide biosynthetic processIDA NASbiological_process
GO:0009897External side of plasma membraneIDAcellular_component
GO:0009986Cell surfaceIEAcellular_component
GO:0016021Integral component of membraneIEAcellular_component
GO:0016323Basolateral plasma membraneIDAcellular_component
GO:0016757Transferase activity, transferring glycosyl groupsIEAmolecular_function
GO:0018146Keratan sulfate biosynthetic processTASbiological_process
GO:0018279Protein N-linked glycosylation via asparagineTASbiological_process
GO:0030057DesmosomeIDAcellular_component
GO:0030112GlycocalyxIDAcellular_component
GO:0030145Manganese ion bindingIDAmolecular_function
GO:0030198Extracellular matrix organizationIEAbiological_process
GO:0030203Glycosaminoglycan metabolic processTASbiological_process
GO:0030879Mammary gland developmentIEAbiological_process
GO:0031526Brush border membraneIDAcellular_component
GO:0032504Multicellular organism reproductionTASbiological_process
GO:0032580Golgi cisterna membraneIEAcellular_component
GO:0035250UDP-galactosyltransferase activityIDAmolecular_function
GO:0042339Keratan sulfate metabolic processTASbiological_process
GO:0042803Protein homodimerization activityIDAmolecular_function
GO:0043014Alpha-tubulin bindingIDAmolecular_function
GO:0043687Post-translational protein modificationTASbiological_process
GO:0044267Cellular protein metabolic processTASbiological_process
GO:0044281Small molecule metabolic processTASbiological_process
GO:0045136Development of secondary sexual characteristicsIEAbiological_process
GO:0048487Beta-tubulin bindingIPImolecular_function
GO:0048754Branching morphogenesis of an epithelial tubeIEAbiological_process
GO:0050900Leukocyte migrationIEAbiological_process
GO:0051270Regulation of cellular component movementIEAbiological_process
GO:0060046Regulation of acrosome reactionIEAbiological_process
GO:0060054Positive regulation of epithelial cell proliferation involved in wound healingIEAbiological_process
GO:0060055Angiogenesis involved in wound healingIEAbiological_process
GO:0060058Positive regulation of apoptotic process involved in mammary gland involutionIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.15667201470.54108726490.78577822031.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.4092006276
GSE13712_SHEARDown-0.1308369563
GSE13712_STATICDown-0.6376721278
GSE19018Up0.0048341439
GSE19899_A1Up0.0267032750
GSE19899_A2Up0.4216330031
PubMed_21979375_A1Up0.4659777066
PubMed_21979375_A2Up0.0947911156
GSE35957Up0.8898093385
GSE36640Down-0.0118824604
GSE54402Down-0.2855206066
GSE9593Down-0.1157483289
GSE43922Up0.5252152681
GSE24585Up0.0796398878
GSE37065Up0.1380352924
GSE28863_A1Up0.7138710453
GSE28863_A2Down-0.0069392950
GSE28863_A3Up0.1268363468
GSE28863_A4Down-0.0482878963
GSE48662Down-0.0176540716

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

N-Acetyl-D-glucosamineDB00141 NUTR00040
6-Aminohexyl-Uridine-C1,5'-DiphosphateDB02696 EXPT03171
Di(N-Acetyl-D-Glucosamine)DB03013 EXPT00851
Uridine-5'-MonophosphateDB03685 EXPT03155
2-(N-Morpholino)-Ethanesulfonic AcidDB03814 EXPT02154

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-124-3pMIMAT0000422MIRT002675MicroarrayFunctional MTI (Weak)15685193
hsa-miR-124-3pMIMAT0000422MIRT002675MicroarrayFunctional MTI (Weak)18668037
hsa-miR-155-5pMIMAT0000646MIRT020817ProteomicsFunctional MTI (Weak)18668040
hsa-miR-128-3pMIMAT0000424MIRT021980MicroarrayFunctional MTI (Weak)17612493
hsa-miR-122-5pMIMAT0000421MIRT023282MicroarrayFunctional MTI (Weak)17612493
hsa-miR-1MIMAT0000416MIRT023802ProteomicsFunctional MTI (Weak)18668040
hsa-miR-16-5pMIMAT0000069MIRT031774ProteomicsFunctional MTI (Weak)18668040
hsa-miR-484MIMAT0002174MIRT042255CLASHFunctional MTI (Weak)23622248
hsa-miR-15b-5pMIMAT0000417MIRT046468CLASHFunctional MTI (Weak)23622248
hsa-miR-18a-5pMIMAT0000072MIRT050738CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.