HCSGD entry for GGCX


1. General information

Official gene symbolGGCX
Entrez ID2677
Gene full namegamma-glutamyl carboxylase
Other gene symbolsVKCFD1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005789Endoplasmic reticulum membraneTAScellular_component
GO:0006464Cellular protein modification processTASbiological_process
GO:0007596Blood coagulationTASbiological_process
GO:0008488Gamma-glutamyl carboxylase activityIEAmolecular_function
GO:0016020MembraneTAScellular_component
GO:0016021Integral component of membraneIEAcellular_component
GO:0017187Peptidyl-glutamic acid carboxylationIEA TASbiological_process
GO:0043687Post-translational protein modificationTASbiological_process
GO:0044267Cellular protein metabolic processTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.78229771290.10125220930.99999024730.6092957019

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1666704920
GSE13712_SHEARDown-0.0551631621
GSE13712_STATICDown-0.1864623248
GSE19018Down-0.1629752313
GSE19899_A1Down-0.1823563744
GSE19899_A2Up0.1402977702
PubMed_21979375_A1Up0.2476946917
PubMed_21979375_A2Down-0.5376871146
GSE35957Down-0.6546479441
GSE36640Up0.4534946389
GSE54402Down-0.2069629183
GSE9593Up0.1549114392
GSE43922Down-0.0326074689
GSE24585Up0.2317876467
GSE37065Down-0.2955115852
GSE28863_A1Up0.1761077766
GSE28863_A2Up0.3695322474
GSE28863_A3Down-0.5583268356
GSE28863_A4Down-0.6087100673
GSE48662Up0.1356043541

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

Coagulation factor VIIa Recombinant HumanDB00036 BTD00006 | BIOD00006
Coagulation Factor IX (Recombinant)DB00100 BTD00038 | BIOD00038
L-Glutamic AcidDB00142 NUTR00027
MenadioneDB00170 NUTR00062

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.