HCSGD entry for GFRA2
1. General information
| Official gene symbol | GFRA2 |
|---|---|
| Entrez ID | 2675 |
| Gene full name | GDNF family receptor alpha 2 |
| Other gene symbols | GDNFRB NRTNR-ALPHA NTNRA RETL2 TRNR2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005886 | Plasma membrane | IEA | cellular_component |
| GO:0007169 | Transmembrane receptor protein tyrosine kinase signaling pathway | TAS | biological_process |
| GO:0007399 | Nervous system development | IEA | biological_process |
| GO:0016167 | Glial cell-derived neurotrophic factor receptor activity | IEA | molecular_function |
| GO:0019221 | Cytokine-mediated signaling pathway | TAS | biological_process |
| GO:0019898 | Extrinsic component of membrane | TAS | cellular_component |
| GO:0031225 | Anchored component of membrane | IEA | cellular_component |
| GO:0031953 | Negative regulation of protein autophosphorylation | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9127895939 | 0.3712044299 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0176070406 |
| GSE13712_SHEAR | Up | 0.1226772576 |
| GSE13712_STATIC | Down | -0.1022331760 |
| GSE19018 | Down | -0.0033588473 |
| GSE19899_A1 | Up | 0.0625631783 |
| GSE19899_A2 | Up | 0.0680746141 |
| PubMed_21979375_A1 | Down | -0.0184324429 |
| PubMed_21979375_A2 | Down | -0.0133846169 |
| GSE35957 | Down | -0.0055139179 |
| GSE36640 | Down | -0.0288016751 |
| GSE54402 | Down | -0.1049201684 |
| GSE9593 | Up | 0.0865784723 |
| GSE43922 | Up | 0.0239200487 |
| GSE24585 | Down | -0.3464658902 |
| GSE37065 | Up | 0.0057872976 |
| GSE28863_A1 | Down | -0.2480604387 |
| GSE28863_A2 | Down | -0.2810323497 |
| GSE28863_A3 | Up | 0.0697241096 |
| GSE28863_A4 | Down | -0.0642024084 |
| GSE48662 | Up | 0.1408462659 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
