HCSGD entry for GFRA2


1. General information

Official gene symbolGFRA2
Entrez ID2675
Gene full nameGDNF family receptor alpha 2
Other gene symbolsGDNFRB NRTNR-ALPHA NTNRA RETL2 TRNR2
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005886Plasma membraneIEAcellular_component
GO:0007169Transmembrane receptor protein tyrosine kinase signaling pathwayTASbiological_process
GO:0007399Nervous system developmentIEAbiological_process
GO:0016167Glial cell-derived neurotrophic factor receptor activityIEAmolecular_function
GO:0019221Cytokine-mediated signaling pathwayTASbiological_process
GO:0019898Extrinsic component of membraneTAScellular_component
GO:0031225Anchored component of membraneIEAcellular_component
GO:0031953Negative regulation of protein autophosphorylationIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.91278959390.37120442990.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0176070406
GSE13712_SHEARUp0.1226772576
GSE13712_STATICDown-0.1022331760
GSE19018Down-0.0033588473
GSE19899_A1Up0.0625631783
GSE19899_A2Up0.0680746141
PubMed_21979375_A1Down-0.0184324429
PubMed_21979375_A2Down-0.0133846169
GSE35957Down-0.0055139179
GSE36640Down-0.0288016751
GSE54402Down-0.1049201684
GSE9593Up0.0865784723
GSE43922Up0.0239200487
GSE24585Down-0.3464658902
GSE37065Up0.0057872976
GSE28863_A1Down-0.2480604387
GSE28863_A2Down-0.2810323497
GSE28863_A3Up0.0697241096
GSE28863_A4Down-0.0642024084
GSE48662Up0.1408462659

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.