HCSGD entry for SLC39A6

1. General information

Official gene symbolSLC39A6
Entrez ID25800
Gene full namesolute carrier family 39 (zinc transporter), member 6
Other gene symbolsLIV-1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005385Zinc ion transmembrane transporter activityIDAmolecular_function
GO:0005783Endoplasmic reticulumIEAcellular_component
GO:0005886Plasma membraneIDA TAScellular_component
GO:0005887Integral component of plasma membraneIDAcellular_component
GO:0006882Cellular zinc ion homeostasisIDAbiological_process
GO:0016020MembraneIEAcellular_component
GO:0031258Lamellipodium membraneIDAcellular_component
GO:0046873Metal ion transmembrane transporter activityIEAmolecular_function
GO:0055085Transmembrane transportTASbiological_process
GO:0071577Zinc ion transmembrane transportIMPbiological_process
GO:0071578Zinc ion transmembrane importIDAbiological_process
GO:0072511Divalent inorganic cation transportIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.23388192320.24564165880.91763380370.9538999852

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1731619024
GSE13712_SHEARUp0.5789277771
GSE13712_STATICUp0.2904106991
GSE19018Down-0.5752456146
GSE19899_A1Down-0.1513243175
GSE19899_A2Down-0.2747672519
PubMed_21979375_A1Up0.2378519861
PubMed_21979375_A2Down-0.0712924446
GSE35957Up0.4958995619
GSE36640Up0.4029125848
GSE54402Down-0.3143286466
GSE9593Up0.6177309299
GSE43922Up0.2345931011
GSE24585Down-0.4686056121
GSE37065Up0.1104736868
GSE28863_A1Down-0.3626268041
GSE28863_A2Up0.3124780496
GSE28863_A3Down-0.6098864202
GSE28863_A4Up0.0838768860
GSE48662Down-0.1889836382

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-32-5pMIMAT0000090MIRT028339SequencingFunctional MTI (Weak)20371350
hsa-miR-26b-5pMIMAT0000083MIRT029131MicroarrayFunctional MTI (Weak)19088304
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.