HCSGD entry for SLC39A6

1. General information

Official gene symbolSLC39A6
Entrez ID25800
Gene full namesolute carrier family 39 (zinc transporter), member 6
Other gene symbolsLIV-1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005385Zinc ion transmembrane transporter activityIDAmolecular_function
GO:0005783Endoplasmic reticulumIEAcellular_component
GO:0005886Plasma membraneIDA TAScellular_component
GO:0005887Integral component of plasma membraneIDAcellular_component
GO:0006882Cellular zinc ion homeostasisIDAbiological_process
GO:0016020MembraneIEAcellular_component
GO:0031258Lamellipodium membraneIDAcellular_component
GO:0046873Metal ion transmembrane transporter activityIEAmolecular_function
GO:0055085Transmembrane transportTASbiological_process
GO:0071577Zinc ion transmembrane transportIMPbiological_process
GO:0071578Zinc ion transmembrane importIDAbiological_process
GO:0072511Divalent inorganic cation transportIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.23388192320.24564165880.91763380370.9538999852

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1731619024
GSE13712_SHEARUp0.5789277771
GSE13712_STATICUp0.2904106991
GSE19018Down-0.5752456146
GSE19899_A1Down-0.1513243175
GSE19899_A2Down-0.2747672519
PubMed_21979375_A1Up0.2378519861
PubMed_21979375_A2Down-0.0712924446
GSE35957Up0.4958995619
GSE36640Up0.4029125848
GSE54402Down-0.3143286466
GSE9593Up0.6177309299
GSE43922Up0.2345931011
GSE24585Down-0.4686056121
GSE37065Up0.1104736868
GSE28863_A1Down-0.3626268041
GSE28863_A2Up0.3124780496
GSE28863_A3Down-0.6098864202
GSE28863_A4Up0.0838768860
GSE48662Down-0.1889836382

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-32-5pMIMAT0000090MIRT028339SequencingFunctional MTI (Weak)20371350
hsa-miR-26b-5pMIMAT0000083MIRT029131MicroarrayFunctional MTI (Weak)19088304
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.