HCSGD entry for GABRG2

1. General information

Official gene symbolGABRG2
Entrez ID2566
Gene full namegamma-aminobutyric acid (GABA) A receptor, gamma 2
Other gene symbolsCAE2 ECA2 GEFSP3
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004890GABA-A receptor activityIEAmolecular_function
GO:0005230Extracellular ligand-gated ion channel activityIEAmolecular_function
GO:0005254Chloride channel activityIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005737CytoplasmIEAcellular_component
GO:0005886Plasma membraneIEA TAScellular_component
GO:0005887Integral component of plasma membraneTAScellular_component
GO:0006810TransportTASbiological_process
GO:0006821Chloride transportIEAbiological_process
GO:0007214Gamma-aminobutyric acid signaling pathwayIEAbiological_process
GO:0007268Synaptic transmissionTASbiological_process
GO:0008503Benzodiazepine receptor activityTASmolecular_function
GO:0009791Post-embryonic developmentIEAbiological_process
GO:0016021Integral component of membraneIEAcellular_component
GO:0030054Cell junctionIEAcellular_component
GO:0030424AxonIEAcellular_component
GO:0030534Adult behaviorIEAbiological_process
GO:0032590Dendrite membraneISScellular_component
GO:0034220Ion transmembrane transportTASbiological_process
GO:0034707Chloride channel complexIEAcellular_component
GO:0045202SynapseIEAcellular_component
GO:0045211Postsynaptic membraneIEAcellular_component
GO:0051932Synaptic transmission, GABAergicISSbiological_process
GO:0055085Transmembrane transportTASbiological_process
GO:0060077Inhibitory synapseIEAcellular_component
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.72259594620.89008677860.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0617401160
GSE13712_SHEARDown-0.0258006331
GSE13712_STATICDown-0.0252426915
GSE19018Down-0.1134481237
GSE19899_A1Up0.0362021202
GSE19899_A2Up0.1448728252
PubMed_21979375_A1Up0.1868947347
PubMed_21979375_A2Up0.1652481437
GSE35957Up0.2490185432
GSE36640Up0.0058299604
GSE54402Up0.0624515487
GSE9593Up0.0347026647
GSE43922Up0.0180744234
GSE24585Up0.0492167664
GSE37065Down-0.1969707460
GSE28863_A1Down-0.0201069680
GSE28863_A2Up0.0875261766
GSE28863_A3Up0.0200673464
GSE28863_A4Up0.0573706783
GSE48662Down-0.0274653641

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.