HCSGD entry for GAB1


1. General information

Official gene symbolGAB1
Entrez ID2549
Gene full nameGRB2-associated binding protein 1
Other gene symbols
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004871Signal transducer activityIEAmolecular_function
GO:0005070SH3/SH2 adaptor activityTASmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005737CytoplasmIEAcellular_component
GO:0005829CytosolTAScellular_component
GO:0006979Response to oxidative stressIEAbiological_process
GO:0007173Epidermal growth factor receptor signaling pathwayIEA TASbiological_process
GO:0007257Activation of JUN kinase activityIEAbiological_process
GO:0007507Heart developmentIEAbiological_process
GO:0008283Cell proliferationTASbiological_process
GO:0008286Insulin receptor signaling pathwayTASbiological_process
GO:0008543Fibroblast growth factor receptor signaling pathwayTASbiological_process
GO:0008544Epidermis developmentIEAbiological_process
GO:0030334Regulation of cell migrationIEAbiological_process
GO:0038095Fc-epsilon receptor signaling pathwayTASbiological_process
GO:0045087Innate immune responseTASbiological_process
GO:0048008Platelet-derived growth factor receptor signaling pathwayIEAbiological_process
GO:0048011Neurotrophin TRK receptor signaling pathwayTASbiological_process
GO:0048015Phosphatidylinositol-mediated signalingTASbiological_process
GO:0060711Labyrinthine layer developmentIEAbiological_process
GO:0070102Interleukin-6-mediated signaling pathwayIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.97472023100.04546117170.99999024730.4004980254

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.3622707225
GSE13712_SHEARDown-0.4986035956
GSE13712_STATICDown-1.1332870799
GSE19018Up0.1369331367
GSE19899_A1Down-0.1869021723
GSE19899_A2Down-0.6369764713
PubMed_21979375_A1Down-0.1719239703
PubMed_21979375_A2Down-0.2823292011
GSE35957Down-0.1606996812
GSE36640Down-0.1807968468
GSE54402Down-0.2788096176
GSE9593Up0.1251135505
GSE43922Down-0.2617345965
GSE24585Up0.2022190405
GSE37065Up0.1375682788
GSE28863_A1Up0.1294535645
GSE28863_A2Down-0.0126387853
GSE28863_A3Up0.0557380439
GSE28863_A4Down-0.1337316847
GSE48662Down-0.0389507147

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-181d-5pMIMAT0002821MIRT041177CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.