HCSGD entry for GAA

1. General information

Official gene symbolGAA
Entrez ID2548
Gene full nameglucosidase, alpha; acid
Other gene symbolsLYAG
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000023Maltose metabolic processICbiological_process
GO:0002026Regulation of the force of heart contractionIEAbiological_process
GO:0002086Diaphragm contractionIEA IMPbiological_process
GO:0003007Heart morphogenesisIEAbiological_process
GO:0004553Hydrolase activity, hydrolyzing O-glycosyl compoundsIEAmolecular_function
GO:0004558Alpha-glucosidase activityIDA IEAmolecular_function
GO:0005764LysosomeIDAcellular_component
GO:0005765Lysosomal membraneIDAcellular_component
GO:0005975Carbohydrate metabolic processIEAbiological_process
GO:0005980Glycogen catabolic processIDA IEAbiological_process
GO:0005985Sucrose metabolic processICbiological_process
GO:0006006Glucose metabolic processICbiological_process
GO:0007040Lysosome organizationIEA IMPbiological_process
GO:0007517Muscle organ developmentIMPbiological_process
GO:0007626Locomotory behaviorIEAbiological_process
GO:0009888Tissue developmentIEAbiological_process
GO:0030246Carbohydrate bindingIEAmolecular_function
GO:0032450Maltose alpha-glucosidase activityIEAmolecular_function
GO:0043181Vacuolar sequesteringIMPbiological_process
GO:0043587Tongue morphogenesisIMPbiological_process
GO:0046716Muscle cell cellular homeostasisIEAbiological_process
GO:0050884Neuromuscular process controlling postureIEAbiological_process
GO:0050885Neuromuscular process controlling balanceIEAbiological_process
GO:0055010Ventricular cardiac muscle tissue morphogenesisIMPbiological_process
GO:0060048Cardiac muscle contractionIMPbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.03855820070.38022467610.44418298341.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1965598469
GSE13712_SHEARUp0.0525923955
GSE13712_STATICUp0.6789301428
GSE19018Up0.0763389003
GSE19899_A1Down-0.1699733007
GSE19899_A2Down-0.5827811762
PubMed_21979375_A1Down-0.1750436410
PubMed_21979375_A2Up0.0144209995
GSE35957Up0.1099963347
GSE36640Up0.4947387802
GSE54402Down-0.2415171764
GSE9593Up0.4579032307
GSE43922Up0.0494772642
GSE24585Down-0.1361139699
GSE37065Down-0.2099882161
GSE28863_A1Up0.7360897811
GSE28863_A2Up0.8349974573
GSE28863_A3Up0.5408749388
GSE28863_A4Down-0.0275084996
GSE48662Up0.6887765012

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

AcarboseDB00284 APRD00656
MiglitolDB00491 APRD01117
AT2220DB05200 -

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.