HCSGD entry for GAA

1. General information

Official gene symbolGAA
Entrez ID2548
Gene full nameglucosidase, alpha; acid
Other gene symbolsLYAG
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000023Maltose metabolic processICbiological_process
GO:0002026Regulation of the force of heart contractionIEAbiological_process
GO:0002086Diaphragm contractionIEA IMPbiological_process
GO:0003007Heart morphogenesisIEAbiological_process
GO:0004553Hydrolase activity, hydrolyzing O-glycosyl compoundsIEAmolecular_function
GO:0004558Alpha-glucosidase activityIDA IEAmolecular_function
GO:0005764LysosomeIDAcellular_component
GO:0005765Lysosomal membraneIDAcellular_component
GO:0005975Carbohydrate metabolic processIEAbiological_process
GO:0005980Glycogen catabolic processIDA IEAbiological_process
GO:0005985Sucrose metabolic processICbiological_process
GO:0006006Glucose metabolic processICbiological_process
GO:0007040Lysosome organizationIEA IMPbiological_process
GO:0007517Muscle organ developmentIMPbiological_process
GO:0007626Locomotory behaviorIEAbiological_process
GO:0009888Tissue developmentIEAbiological_process
GO:0030246Carbohydrate bindingIEAmolecular_function
GO:0032450Maltose alpha-glucosidase activityIEAmolecular_function
GO:0043181Vacuolar sequesteringIMPbiological_process
GO:0043587Tongue morphogenesisIMPbiological_process
GO:0046716Muscle cell cellular homeostasisIEAbiological_process
GO:0050884Neuromuscular process controlling postureIEAbiological_process
GO:0050885Neuromuscular process controlling balanceIEAbiological_process
GO:0055010Ventricular cardiac muscle tissue morphogenesisIMPbiological_process
GO:0060048Cardiac muscle contractionIMPbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.03855820070.38022467610.44418298341.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1965598469
GSE13712_SHEARUp0.0525923955
GSE13712_STATICUp0.6789301428
GSE19018Up0.0763389003
GSE19899_A1Down-0.1699733007
GSE19899_A2Down-0.5827811762
PubMed_21979375_A1Down-0.1750436410
PubMed_21979375_A2Up0.0144209995
GSE35957Up0.1099963347
GSE36640Up0.4947387802
GSE54402Down-0.2415171764
GSE9593Up0.4579032307
GSE43922Up0.0494772642
GSE24585Down-0.1361139699
GSE37065Down-0.2099882161
GSE28863_A1Up0.7360897811
GSE28863_A2Up0.8349974573
GSE28863_A3Up0.5408749388
GSE28863_A4Down-0.0275084996
GSE48662Up0.6887765012

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

AcarboseDB00284 APRD00656
MiglitolDB00491 APRD01117
AT2220DB05200 -

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.