HCSGD entry for FZD2

1. General information

Official gene symbolFZD2
Entrez ID2535
Gene full namefrizzled family receptor 2
Other gene symbolsFz2 fz-2 fzE2 hFz2
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001944Vasculature developmentIBAbiological_process
GO:0003149Membranous septum morphogenesisIEAbiological_process
GO:0003150Muscular septum morphogenesisIEAbiological_process
GO:0003151Outflow tract morphogenesisIEAbiological_process
GO:0004930G-protein coupled receptor activityIEAmolecular_function
GO:0005737CytoplasmIDAcellular_component
GO:0005886Plasma membraneIDAcellular_component
GO:0007199G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messengerIBAbiological_process
GO:0007223Wnt signaling pathway, calcium modulating pathwayIBAbiological_process
GO:0007267Cell-cell signalingIEAbiological_process
GO:0007409AxonogenesisIBAbiological_process
GO:0007420Brain developmentIBAbiological_process
GO:0007608Sensory perception of smellIEAbiological_process
GO:0008406Gonad developmentIBAbiological_process
GO:0009790Embryo developmentIBAbiological_process
GO:0016021Integral component of membraneIEAcellular_component
GO:0017147Wnt-protein bindingIBAmolecular_function
GO:0030165PDZ domain bindingIPImolecular_function
GO:0030182Neuron differentiationISSbiological_process
GO:0030825Positive regulation of cGMP metabolic processIMPbiological_process
GO:0030855Epithelial cell differentiationIBAbiological_process
GO:0032589Neuron projection membraneIBAcellular_component
GO:0042813Wnt-activated receptor activityIBAmolecular_function
GO:0045177Apical part of cellIBAcellular_component
GO:0045893Positive regulation of transcription, DNA-templatedIDAbiological_process
GO:0051091Positive regulation of sequence-specific DNA binding transcription factor activityIDAbiological_process
GO:0060022Hard palate developmentIEAbiological_process
GO:0060070Canonical Wnt signaling pathwayIDAbiological_process
GO:0060119Inner ear receptor cell developmentIEAbiological_process
GO:0090103Cochlea morphogenesisIEAbiological_process
GO:0090179Planar cell polarity pathway involved in neural tube closureIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.93462844500.00018588960.99999024730.0245860000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.9614132837
GSE13712_SHEARDown-1.2852505422
GSE13712_STATICDown-1.2803894246
GSE19018Up0.4208603887
GSE19899_A1Down-2.5217093962
GSE19899_A2Down-3.8353728368
PubMed_21979375_A1Down-1.9234630955
PubMed_21979375_A2Down-4.8629921079
GSE35957Up0.9924916782
GSE36640Down-0.6075708756
GSE54402Down-1.3677056412
GSE9593Up0.5944330703
GSE43922Down-2.0030817451
GSE24585Up0.2080122447
GSE37065Down-0.3804744402
GSE28863_A1Down-0.2191689126
GSE28863_A2Up0.0878430868
GSE28863_A3Down-0.0591281222
GSE28863_A4Down-0.0470897773
GSE48662Down-0.2384374306

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.