HCSGD entry for FZD2

1. General information

Official gene symbolFZD2
Entrez ID2535
Gene full namefrizzled family receptor 2
Other gene symbolsFz2 fz-2 fzE2 hFz2
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001944Vasculature developmentIBAbiological_process
GO:0003149Membranous septum morphogenesisIEAbiological_process
GO:0003150Muscular septum morphogenesisIEAbiological_process
GO:0003151Outflow tract morphogenesisIEAbiological_process
GO:0004930G-protein coupled receptor activityIEAmolecular_function
GO:0005737CytoplasmIDAcellular_component
GO:0005886Plasma membraneIDAcellular_component
GO:0007199G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messengerIBAbiological_process
GO:0007223Wnt signaling pathway, calcium modulating pathwayIBAbiological_process
GO:0007267Cell-cell signalingIEAbiological_process
GO:0007409AxonogenesisIBAbiological_process
GO:0007420Brain developmentIBAbiological_process
GO:0007608Sensory perception of smellIEAbiological_process
GO:0008406Gonad developmentIBAbiological_process
GO:0009790Embryo developmentIBAbiological_process
GO:0016021Integral component of membraneIEAcellular_component
GO:0017147Wnt-protein bindingIBAmolecular_function
GO:0030165PDZ domain bindingIPImolecular_function
GO:0030182Neuron differentiationISSbiological_process
GO:0030825Positive regulation of cGMP metabolic processIMPbiological_process
GO:0030855Epithelial cell differentiationIBAbiological_process
GO:0032589Neuron projection membraneIBAcellular_component
GO:0042813Wnt-activated receptor activityIBAmolecular_function
GO:0045177Apical part of cellIBAcellular_component
GO:0045893Positive regulation of transcription, DNA-templatedIDAbiological_process
GO:0051091Positive regulation of sequence-specific DNA binding transcription factor activityIDAbiological_process
GO:0060022Hard palate developmentIEAbiological_process
GO:0060070Canonical Wnt signaling pathwayIDAbiological_process
GO:0060119Inner ear receptor cell developmentIEAbiological_process
GO:0090103Cochlea morphogenesisIEAbiological_process
GO:0090179Planar cell polarity pathway involved in neural tube closureIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.93462844500.00018588960.99999024730.0245860000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.9614132837
GSE13712_SHEARDown-1.2852505422
GSE13712_STATICDown-1.2803894246
GSE19018Up0.4208603887
GSE19899_A1Down-2.5217093962
GSE19899_A2Down-3.8353728368
PubMed_21979375_A1Down-1.9234630955
PubMed_21979375_A2Down-4.8629921079
GSE35957Up0.9924916782
GSE36640Down-0.6075708756
GSE54402Down-1.3677056412
GSE9593Up0.5944330703
GSE43922Down-2.0030817451
GSE24585Up0.2080122447
GSE37065Down-0.3804744402
GSE28863_A1Down-0.2191689126
GSE28863_A2Up0.0878430868
GSE28863_A3Down-0.0591281222
GSE28863_A4Down-0.0470897773
GSE48662Down-0.2384374306

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.